Nodular Subcutaneous Phaeohyphomycosis due to Medicopsis romeroi in an Immunocompetent Patient
Fungal infections like subcutaneous phaeohyphomycosis are uncommon but are increasing lately, especially in tropical regions like India. Identification of correct aetiologic agent is essential as different species can have different organ tropism. Here, a rare case of nodular subcutaneous phaeohyp...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2021-08-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/15244/50213_CE[Ra1]_F[SK]_PF1(AG_OM)_PFA(KM)_PB(AG_KM)_PN(KM).pdf |
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| author | Smita Deshkar Niranjan Patil Ashish Lad Shraddha Amberkar Swati Sharan |
| author_facet | Smita Deshkar Niranjan Patil Ashish Lad Shraddha Amberkar Swati Sharan |
| author_sort | Smita Deshkar |
| collection | DOAJ |
| description | Fungal infections like subcutaneous phaeohyphomycosis are uncommon but are increasing lately, especially in tropical regions
like India. Identification of correct aetiologic agent is essential as different species can have different organ tropism. Here, a rare
case of nodular subcutaneous phaeohyphomycosis in an immunocompetent 62-year-old male patient who developed nodule over
right dorsum of foot is reported. After various diagnostic tests a rare dematiaceous fungus Medicopsis romeroi was identified
as a causative agent in the nodular material by Internal Transcribed Spacer (ITS) sequencing. Surgical excision and antifungal
therapy of itraconazole proved beneficial with no recurrence during a six months of follow-up. Medicopsis romeroi has been
debated for its role in human infections however, it should be considered as one of the aetiologic agents of subcutaneous
phaeohyphomycosis. |
| first_indexed | 2024-12-21T06:21:21Z |
| format | Article |
| id | doaj.art-dcc2fe9e6cc246018a97fb2cc525c8be |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-21T06:21:21Z |
| publishDate | 2021-08-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-dcc2fe9e6cc246018a97fb2cc525c8be2022-12-21T19:13:14ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2021-08-01158DD01DD0310.7860/JCDR/2021/50213.15244Nodular Subcutaneous Phaeohyphomycosis due to Medicopsis romeroi in an Immunocompetent PatientSmita Deshkar0Niranjan Patil1Ashish Lad2Shraddha Amberkar3Swati Sharan4Microbiologist, Department of Microbiology and Molecular Biology, Metropolis Healthcare Limited, Mumbai, Maharashtra, India.Head, Department of Microbiology and Molecular Biology, Metropolis Healthcare Limited, Mumbai, Maharashtra, India.Senior Laboratory Manager, Department of Microbiology and Molecular Biology, Metropolis Healthcare Limited, Mumbai, Maharashtra, India.Section Head, Department of Microbiology, Metropolis Healthcare Limited, Mumbai, Maharashtra, India.Senior Scientific Officer, Department of Molecular Biology, Metropolis Healthcare Limited, Mumbai, Maharashtra, India.Fungal infections like subcutaneous phaeohyphomycosis are uncommon but are increasing lately, especially in tropical regions like India. Identification of correct aetiologic agent is essential as different species can have different organ tropism. Here, a rare case of nodular subcutaneous phaeohyphomycosis in an immunocompetent 62-year-old male patient who developed nodule over right dorsum of foot is reported. After various diagnostic tests a rare dematiaceous fungus Medicopsis romeroi was identified as a causative agent in the nodular material by Internal Transcribed Spacer (ITS) sequencing. Surgical excision and antifungal therapy of itraconazole proved beneficial with no recurrence during a six months of follow-up. Medicopsis romeroi has been debated for its role in human infections however, it should be considered as one of the aetiologic agents of subcutaneous phaeohyphomycosis.https://jcdr.net/articles/PDF/15244/50213_CE[Ra1]_F[SK]_PF1(AG_OM)_PFA(KM)_PB(AG_KM)_PN(KM).pdffungal infectioninternal transcribed spacer sequencingitraconazole |
| spellingShingle | Smita Deshkar Niranjan Patil Ashish Lad Shraddha Amberkar Swati Sharan Nodular Subcutaneous Phaeohyphomycosis due to Medicopsis romeroi in an Immunocompetent Patient Journal of Clinical and Diagnostic Research fungal infection internal transcribed spacer sequencing itraconazole |
| title | Nodular Subcutaneous Phaeohyphomycosis due to Medicopsis romeroi in an Immunocompetent Patient |
| title_full | Nodular Subcutaneous Phaeohyphomycosis due to Medicopsis romeroi in an Immunocompetent Patient |
| title_fullStr | Nodular Subcutaneous Phaeohyphomycosis due to Medicopsis romeroi in an Immunocompetent Patient |
| title_full_unstemmed | Nodular Subcutaneous Phaeohyphomycosis due to Medicopsis romeroi in an Immunocompetent Patient |
| title_short | Nodular Subcutaneous Phaeohyphomycosis due to Medicopsis romeroi in an Immunocompetent Patient |
| title_sort | nodular subcutaneous phaeohyphomycosis due to medicopsis romeroi in an immunocompetent patient |
| topic | fungal infection internal transcribed spacer sequencing itraconazole |
| url | https://jcdr.net/articles/PDF/15244/50213_CE[Ra1]_F[SK]_PF1(AG_OM)_PFA(KM)_PB(AG_KM)_PN(KM).pdf |
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