Effect of taxifolin on methotrexate-induced oxidative and inflammatory oral mucositis in rats: biochemical and histopathological evaluation

Effect of taxifolin on methotrexate-induced oxidative and inflammatory oral mucositis in rats: biochemical and histopathological evaluation

Abstract The role of oxidative stress, as well as inflammation in the pathogenesis of methotrexate (MTX)-induced oral mucositis, is a known fact. The anti-inflammatory, antitumor, antimicrobial, and antioxidant properties of taxifolin—the effect we tested against MTX-induced oral mucosal damage—are...

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Bibliographic Details
Main Authors: Zeynep BAYRAMOGLU, Behzad MOKHTARE, Ali Sefa MENDIL, Taha Abdulkadir COBAN, Renad MAMMADOV, Seval BULUT, Zeynep SULEYMAN, Halis SULEYMAN
Format: Article
Language:English
Published: University of São Paulo 2022-09-01
Series:Journal of Applied Oral Science
Subjects:
Taxifolin
Methotrexate
Oral mucositis
Rat
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572022000100437&tlng=en

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