Determining the Radiation Enhancement Effects of Gold Nanoparticles in Cells in a Combined Treatment with Cisplatin and Radiation at Therapeutic Megavoltage Energies

Determining the Radiation Enhancement Effects of Gold Nanoparticles in Cells in a Combined Treatment with Cisplatin and Radiation at Therapeutic Megavoltage Energies

Combined use of chemotherapy and radiation therapy is commonly used in cancer treatment, but the toxic effects on normal tissue are a major limitation. This study assesses the potential to improve radiation therapy when combining gold nanoparticle (GNP) mediated radiation sensitization with chemorad...

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Bibliographic Details
Main Authors: Celina Yang, Kyle Bromma, Wonmo Sung, Jan Schuemann, Devika Chithrani
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:Cancers
Subjects:
gold nanoparticles (GNP)
cisplatin
Monte Carlo
radiation
chemoradiation
Online Access:http://www.mdpi.com/2072-6694/10/5/150

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