Native LDL potentiate TNFα and IL-8 production by human mononuclear cells

Native LDL potentiate TNFα and IL-8 production by human mononuclear cells

Native LDL (nLDL) increases expression of adhesion molecules on endothelial cells through induction of Ca2+ mobilization. Ca2+ mobilization is also involved in the induction of proinflammatory cytokines, important mediators involved in atherogenesis. The aim of the study was to evaluate the capacity...

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Bibliographic Details
Main Authors: Mihai G. Netea, Bart Jan Kullberg, Pierre N.M. Demacker, Liesbeth E.H. Jacobs, Trees J.G. Verver-Jansen, Anneke Hijmans, Lambertus H.J. van Tits, Joost G.J. Hoenderop, Peter H.G.M. Willems, Jos W.M. Van der Meer, Anton F.H. Stalenhoef
Format: Article
Language:English
Published: Elsevier 2002-07-01
Series:Journal of Lipid Research
Subjects:
tumor necrosis factor α
interleukin-8
Ca2+ mobilization
low density lipoprotein
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520314681

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