An overview of DNA methylation-derived trait score methods and applications
Abstract Microarray technology has been used to measure genome-wide DNA methylation in thousands of individuals. These studies typically test the associations between individual DNA methylation sites (“probes”) and complex traits or diseases. The results can be used to generate methylation profile s...
Main Authors: | Marta F. Nabais, Danni A. Gadd, Eilis Hannon, Jonathan Mill, Allan F. McRae, Naomi R. Wray |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-02-01
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Series: | Genome Biology |
Online Access: | https://doi.org/10.1186/s13059-023-02855-7 |
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