An overview of DNA methylation-derived trait score methods and applications

Abstract Microarray technology has been used to measure genome-wide DNA methylation in thousands of individuals. These studies typically test the associations between individual DNA methylation sites (“probes”) and complex traits or diseases. The results can be used to generate methylation profile s...

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Bibliographic Details
Main Authors: Marta F. Nabais, Danni A. Gadd, Eilis Hannon, Jonathan Mill, Allan F. McRae, Naomi R. Wray
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Genome Biology
Online Access:https://doi.org/10.1186/s13059-023-02855-7

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