Musculoskeletal ultrasound as a screening-tool for rheumatoid arthritis: results of the “Rheuma-Truck” screening and awareness initiative
Abstract Objective To evaluate musculoskeletal ultrasound (MSUS) as a screening tool for rheumatoid arthritis (RA) and osteoarthritis (OA) patients in a rheumatology-screening program. Patients and methods To raise awareness for rheumatic diseases, a mobile rheumatology office was deployed in differ...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-01-01
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| Series: | Advances in Rheumatology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s42358-021-00233-0 |
| _version_ | 1798034682813612032 |
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| author | Alexander Lautwein Benedikt Ostendorf Stefan Vordenbäumen Aiko Liedmann Ralph Brinks Mario Giulini Sarah Ohrndorf Marina Backhaus Hasan Acar Oliver Sander Jutta G. Richter Matthias Schneider Philipp Sewerin |
| author_facet | Alexander Lautwein Benedikt Ostendorf Stefan Vordenbäumen Aiko Liedmann Ralph Brinks Mario Giulini Sarah Ohrndorf Marina Backhaus Hasan Acar Oliver Sander Jutta G. Richter Matthias Schneider Philipp Sewerin |
| author_sort | Alexander Lautwein |
| collection | DOAJ |
| description | Abstract Objective To evaluate musculoskeletal ultrasound (MSUS) as a screening tool for rheumatoid arthritis (RA) and osteoarthritis (OA) patients in a rheumatology-screening program. Patients and methods To raise awareness for rheumatic diseases, a mobile rheumatology office was deployed in different cities of Germany (“Rheuma-Truck”). Standardized questionnaire assessment, testing for rheumatoid factor and citrullinated peptide antibodies and medical student driven MSUS of the clinically dominant hand/foot including wrist, MCP-II, -III, -V, PIP-II, -III, MTP-II and -V were offered free of charge to the population. In case of suspicious results, a rheumatologist was consulted. Results In MSUS, 192 of 560 selected volunteers (aged 18–89, mean 52.7 years; 72.9% female) had suspicious findings including synovitis or erosions primarily affecting the MTP-II (11.8%), dorsal wrist (8.9%), and MCP-II (7%). 354 of the 560 volunteers further visited a rheumatologist of whom 76 were diagnosed with RA. According to the ‘US7 Score’, a sum scores ≥ 5 was significantly predictive for RA (odds ratio (OR) 5.06; confidence interval (CI) 0.83–35.32). 313 volunteers displayed signs of OA including osteophytes, while MCP-II (36.2%), MCP-III (14.8%), and the wrist (10.5%) were mostly affected. Diagnosis of RA was favoured over OA if the wrist (OR 4.2; CI 1.28–13.95), MTP-II (OR 1.62; CI 1.0–2.6), and MCP-V (OR 2.0; CI 1.0–3.8) were involved. Conclusion Medical student driven MSUS by the ‘US7 Score’ can facilitate diagnosis of RA in rheumatology-screening programs due to the level of the score and the affected joints. A high rate of unknown OA signs was detected by MSUS. A mobile rheumatology office displays an opportunity to screen patients for RA and OA. |
| first_indexed | 2024-04-11T20:47:38Z |
| format | Article |
| id | doaj.art-dcc88fe924ed4869af0e278d31c58e44 |
| institution | Directory Open Access Journal |
| issn | 2523-3106 |
| language | English |
| last_indexed | 2024-04-11T20:47:38Z |
| publishDate | 2022-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Advances in Rheumatology |
| spelling | doaj.art-dcc88fe924ed4869af0e278d31c58e442022-12-22T04:03:58ZengBMCAdvances in Rheumatology2523-31062022-01-016211810.1186/s42358-021-00233-0Musculoskeletal ultrasound as a screening-tool for rheumatoid arthritis: results of the “Rheuma-Truck” screening and awareness initiativeAlexander Lautwein0Benedikt Ostendorf1Stefan Vordenbäumen2Aiko Liedmann3Ralph Brinks4Mario Giulini5Sarah Ohrndorf6Marina Backhaus7Hasan Acar8Oliver Sander9Jutta G. Richter10Matthias Schneider11Philipp Sewerin12Department and Hiller-Research-Unit for Rheumatology, UKD, Heinrich-Heine-University Düsseldorf Medical FacultyDepartment and Hiller-Research-Unit for Rheumatology, UKD, Heinrich-Heine-University Düsseldorf Medical FacultyDepartment and Hiller-Research-Unit for Rheumatology, UKD, Heinrich-Heine-University Düsseldorf Medical FacultyDepartment and Hiller-Research-Unit for Rheumatology, UKD, Heinrich-Heine-University Düsseldorf Medical FacultyDepartment and Hiller-Research-Unit for Rheumatology, UKD, Heinrich-Heine-University Düsseldorf Medical FacultyDepartment and Hiller-Research-Unit for Rheumatology, UKD, Heinrich-Heine-University Düsseldorf Medical FacultyDepartment of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin BerlinDepartment of Internal Medicine, Rheumatology and Clinical Immunology, Academic Hospital of the Charité BerlinDepartment and Hiller-Research-Unit for Rheumatology, UKD, Heinrich-Heine-University Düsseldorf Medical FacultyDepartment and Hiller-Research-Unit for Rheumatology, UKD, Heinrich-Heine-University Düsseldorf Medical FacultyDepartment and Hiller-Research-Unit for Rheumatology, UKD, Heinrich-Heine-University Düsseldorf Medical FacultyDepartment and Hiller-Research-Unit for Rheumatology, UKD, Heinrich-Heine-University Düsseldorf Medical FacultyDepartment and Hiller-Research-Unit for Rheumatology, UKD, Heinrich-Heine-University Düsseldorf Medical FacultyAbstract Objective To evaluate musculoskeletal ultrasound (MSUS) as a screening tool for rheumatoid arthritis (RA) and osteoarthritis (OA) patients in a rheumatology-screening program. Patients and methods To raise awareness for rheumatic diseases, a mobile rheumatology office was deployed in different cities of Germany (“Rheuma-Truck”). Standardized questionnaire assessment, testing for rheumatoid factor and citrullinated peptide antibodies and medical student driven MSUS of the clinically dominant hand/foot including wrist, MCP-II, -III, -V, PIP-II, -III, MTP-II and -V were offered free of charge to the population. In case of suspicious results, a rheumatologist was consulted. Results In MSUS, 192 of 560 selected volunteers (aged 18–89, mean 52.7 years; 72.9% female) had suspicious findings including synovitis or erosions primarily affecting the MTP-II (11.8%), dorsal wrist (8.9%), and MCP-II (7%). 354 of the 560 volunteers further visited a rheumatologist of whom 76 were diagnosed with RA. According to the ‘US7 Score’, a sum scores ≥ 5 was significantly predictive for RA (odds ratio (OR) 5.06; confidence interval (CI) 0.83–35.32). 313 volunteers displayed signs of OA including osteophytes, while MCP-II (36.2%), MCP-III (14.8%), and the wrist (10.5%) were mostly affected. Diagnosis of RA was favoured over OA if the wrist (OR 4.2; CI 1.28–13.95), MTP-II (OR 1.62; CI 1.0–2.6), and MCP-V (OR 2.0; CI 1.0–3.8) were involved. Conclusion Medical student driven MSUS by the ‘US7 Score’ can facilitate diagnosis of RA in rheumatology-screening programs due to the level of the score and the affected joints. A high rate of unknown OA signs was detected by MSUS. A mobile rheumatology office displays an opportunity to screen patients for RA and OA.https://doi.org/10.1186/s42358-021-00233-0Musculoskeletal ultrasoundScreeningRheumatoid arthritisOsteoarthritis |
| spellingShingle | Alexander Lautwein Benedikt Ostendorf Stefan Vordenbäumen Aiko Liedmann Ralph Brinks Mario Giulini Sarah Ohrndorf Marina Backhaus Hasan Acar Oliver Sander Jutta G. Richter Matthias Schneider Philipp Sewerin Musculoskeletal ultrasound as a screening-tool for rheumatoid arthritis: results of the “Rheuma-Truck” screening and awareness initiative Advances in Rheumatology Musculoskeletal ultrasound Screening Rheumatoid arthritis Osteoarthritis |
| title | Musculoskeletal ultrasound as a screening-tool for rheumatoid arthritis: results of the “Rheuma-Truck” screening and awareness initiative |
| title_full | Musculoskeletal ultrasound as a screening-tool for rheumatoid arthritis: results of the “Rheuma-Truck” screening and awareness initiative |
| title_fullStr | Musculoskeletal ultrasound as a screening-tool for rheumatoid arthritis: results of the “Rheuma-Truck” screening and awareness initiative |
| title_full_unstemmed | Musculoskeletal ultrasound as a screening-tool for rheumatoid arthritis: results of the “Rheuma-Truck” screening and awareness initiative |
| title_short | Musculoskeletal ultrasound as a screening-tool for rheumatoid arthritis: results of the “Rheuma-Truck” screening and awareness initiative |
| title_sort | musculoskeletal ultrasound as a screening tool for rheumatoid arthritis results of the rheuma truck screening and awareness initiative |
| topic | Musculoskeletal ultrasound Screening Rheumatoid arthritis Osteoarthritis |
| url | https://doi.org/10.1186/s42358-021-00233-0 |
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