Endovascular Treatment of Vein of Galen Malformation in Kenya, East Africa
Vein of Galen aneurysmal malformations (VGAM) are arteriovenous fistulas between the choroidal or quadrigeminal arteries and the embryonic precursor of the vein of Galen – the median prosencephalic vein. VGAM represents 30% of arteriovenous malformations in the paediatric age group. They are associa...
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| Format: | Article |
| Language: | English |
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Surgical Society of Kenya
2022-07-01
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| Series: | The Annals of African Surgery |
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| Online Access: | https://www.annalsofafricansurgery.com/endovascular-treatment-of-galen-vein |
| _version_ | 1798036537718341632 |
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| author | Edwin Mogere Cecilia Munguti |
| author_facet | Edwin Mogere Cecilia Munguti |
| author_sort | Edwin Mogere |
| collection | DOAJ |
| description | Vein of Galen aneurysmal malformations (VGAM) are arteriovenous fistulas between the choroidal or quadrigeminal arteries and the embryonic precursor of the vein of Galen – the median prosencephalic vein. VGAM represents 30% of arteriovenous malformations in the paediatric age group. They are associated with a high morbidity and 90% mortality if untreated but respond well to intervention with mortality reduced to below 40%. There are few documented cases of VGAM worldwide and scarce data about these lesions in sub-Saharan Africa with challenges in diagnosis and management. We present two cases of infants diagnosed with VGAM and treated with endovascular embolisation. We examine the clinical and radiological data at presentation, intervention and follow-up at one year. We report on some of the technical neuro-interventional details. Both patients had satisfactory radiological results and the interventions resulted notable clinical improvements from baseline. Physicians should maintain a high index of suspicion treating infants and toddlers presenting with macrocephaly, neurocognitive decline and cardiopulmonary symptoms. Upon diagnosis endovascular interventions are feasible and available. |
| first_indexed | 2024-04-11T21:14:17Z |
| format | Article |
| id | doaj.art-dcc8e32d122a46c29fb3fe06f1b80d68 |
| institution | Directory Open Access Journal |
| issn | 1999-9674 2523-0816 |
| language | English |
| last_indexed | 2024-04-11T21:14:17Z |
| publishDate | 2022-07-01 |
| publisher | Surgical Society of Kenya |
| record_format | Article |
| series | The Annals of African Surgery |
| spelling | doaj.art-dcc8e32d122a46c29fb3fe06f1b80d682022-12-22T04:02:53ZengSurgical Society of KenyaThe Annals of African Surgery1999-96742523-08162022-07-01193153157http://dx.doi.org/10.4314/aas.v19i3.4Endovascular Treatment of Vein of Galen Malformation in Kenya, East AfricaEdwin Mogere0https://orcid.org/0000-0002-0180-5746Cecilia Munguti1https://orcid.org/0000-0001-7400-6446Department of Neurosurgery, Aga Khan University Hospital, Nairobi, KenyaDepartment of Neurosurgery, Aga Khan University Hospital, Nairobi, KenyaVein of Galen aneurysmal malformations (VGAM) are arteriovenous fistulas between the choroidal or quadrigeminal arteries and the embryonic precursor of the vein of Galen – the median prosencephalic vein. VGAM represents 30% of arteriovenous malformations in the paediatric age group. They are associated with a high morbidity and 90% mortality if untreated but respond well to intervention with mortality reduced to below 40%. There are few documented cases of VGAM worldwide and scarce data about these lesions in sub-Saharan Africa with challenges in diagnosis and management. We present two cases of infants diagnosed with VGAM and treated with endovascular embolisation. We examine the clinical and radiological data at presentation, intervention and follow-up at one year. We report on some of the technical neuro-interventional details. Both patients had satisfactory radiological results and the interventions resulted notable clinical improvements from baseline. Physicians should maintain a high index of suspicion treating infants and toddlers presenting with macrocephaly, neurocognitive decline and cardiopulmonary symptoms. Upon diagnosis endovascular interventions are feasible and available.https://www.annalsofafricansurgery.com/endovascular-treatment-of-galen-veinendovascularvein of galencoilingembolizationarteriovenous fistula |
| spellingShingle | Edwin Mogere Cecilia Munguti Endovascular Treatment of Vein of Galen Malformation in Kenya, East Africa The Annals of African Surgery endovascular vein of galen coiling embolization arteriovenous fistula |
| title | Endovascular Treatment of Vein of Galen Malformation in Kenya, East Africa |
| title_full | Endovascular Treatment of Vein of Galen Malformation in Kenya, East Africa |
| title_fullStr | Endovascular Treatment of Vein of Galen Malformation in Kenya, East Africa |
| title_full_unstemmed | Endovascular Treatment of Vein of Galen Malformation in Kenya, East Africa |
| title_short | Endovascular Treatment of Vein of Galen Malformation in Kenya, East Africa |
| title_sort | endovascular treatment of vein of galen malformation in kenya east africa |
| topic | endovascular vein of galen coiling embolization arteriovenous fistula |
| url | https://www.annalsofafricansurgery.com/endovascular-treatment-of-galen-vein |
| work_keys_str_mv | AT edwinmogere endovasculartreatmentofveinofgalenmalformationinkenyaeastafrica AT ceciliamunguti endovasculartreatmentofveinofgalenmalformationinkenyaeastafrica |