Accidental severe poisoning with methemoglobinogenic substance: A case report

A 45-year-old male patient was admitted to the Regional Poison Center because of poisoning with dimethyloaniline contained in a toxic resin-curing dimethyl aniline-based formulation ingested inadvertently. Intoxication happened at workplace. The patient was then transferred to the Toxicology Clinic,...

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Main Authors: Kinga Rośniak-Bąk, Marek Bąk, Renata Winnicka, Anna Krakowiak
Format: Article
Language:English
Published: Nofer Institute of Occupational Medicine 2017-12-01
Series:Medycyna Pracy
Subjects:
Online Access:http://medpr.imp.lodz.pl/Zatrucie-substancja-methemoglobinotworcza-no-ciezkim-przebiegu-opis-przypadku,70569,0,2.html
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author Kinga Rośniak-Bąk
Marek Bąk
Renata Winnicka
Anna Krakowiak
author_facet Kinga Rośniak-Bąk
Marek Bąk
Renata Winnicka
Anna Krakowiak
author_sort Kinga Rośniak-Bąk
collection DOAJ
description A 45-year-old male patient was admitted to the Regional Poison Center because of poisoning with dimethyloaniline contained in a toxic resin-curing dimethyl aniline-based formulation ingested inadvertently. Intoxication happened at workplace. The patient was then transferred to the Toxicology Clinic, where he stayed for 3 weeks. During the hospitalization, the primary method of treatment involved administration of methylene blue, which is the antidote of choice in such cases. During the intensive care and treatment of the patient massive intravascular hemolysis was seen. In that case treatment with blood products was required. He also showed signs of liver dysfunction due to cholestatic liver damage and jaundice. The reported case shows that severe organ damage may result from poisoning with even a small amount of the toxicant. Med Pr 2017;68(6):795–801
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spelling doaj.art-dcccf95e72d64791aac6e400234376692022-12-21T19:53:59ZengNofer Institute of Occupational MedicineMedycyna Pracy0465-58932353-13392017-12-01686795801Accidental severe poisoning with methemoglobinogenic substance: A case reportKinga Rośniak-BąkMarek BąkRenata WinnickaAnna KrakowiakA 45-year-old male patient was admitted to the Regional Poison Center because of poisoning with dimethyloaniline contained in a toxic resin-curing dimethyl aniline-based formulation ingested inadvertently. Intoxication happened at workplace. The patient was then transferred to the Toxicology Clinic, where he stayed for 3 weeks. During the hospitalization, the primary method of treatment involved administration of methylene blue, which is the antidote of choice in such cases. During the intensive care and treatment of the patient massive intravascular hemolysis was seen. In that case treatment with blood products was required. He also showed signs of liver dysfunction due to cholestatic liver damage and jaundice. The reported case shows that severe organ damage may result from poisoning with even a small amount of the toxicant. Med Pr 2017;68(6):795–801http://medpr.imp.lodz.pl/Zatrucie-substancja-methemoglobinotworcza-no-ciezkim-przebiegu-opis-przypadku,70569,0,2.htmlintoxicationliver failuremethylene blueanilinehemolysisjaundice
spellingShingle Kinga Rośniak-Bąk
Marek Bąk
Renata Winnicka
Anna Krakowiak
Accidental severe poisoning with methemoglobinogenic substance: A case report
Medycyna Pracy
intoxication
liver failure
methylene blue
aniline
hemolysis
jaundice
title Accidental severe poisoning with methemoglobinogenic substance: A case report
title_full Accidental severe poisoning with methemoglobinogenic substance: A case report
title_fullStr Accidental severe poisoning with methemoglobinogenic substance: A case report
title_full_unstemmed Accidental severe poisoning with methemoglobinogenic substance: A case report
title_short Accidental severe poisoning with methemoglobinogenic substance: A case report
title_sort accidental severe poisoning with methemoglobinogenic substance a case report
topic intoxication
liver failure
methylene blue
aniline
hemolysis
jaundice
url http://medpr.imp.lodz.pl/Zatrucie-substancja-methemoglobinotworcza-no-ciezkim-przebiegu-opis-przypadku,70569,0,2.html
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AT marekbak accidentalseverepoisoningwithmethemoglobinogenicsubstanceacasereport
AT renatawinnicka accidentalseverepoisoningwithmethemoglobinogenicsubstanceacasereport
AT annakrakowiak accidentalseverepoisoningwithmethemoglobinogenicsubstanceacasereport