Papilledema in Space Flight: Pathogenesis, Diagnostics and Monitoring

Some Russian cosmonauts in space flight have revealed swelling of the optic nerve head of varying severity. Four clinical cases presented in this article. A quantitative method for the analysis of OCT images of the optic nerve head and the retina has been developed for the diagnosis and monitoring o...

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Main Authors: I. A. Makarov, S. N. Danilichev
Format: Article
Language:Russian
Published: Ophthalmology Publishing Group 2020-12-01
Series:Oftalʹmologiâ
Subjects:
Online Access:https://www.ophthalmojournal.com/opht/article/view/1369
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author I. A. Makarov
S. N. Danilichev
author_facet I. A. Makarov
S. N. Danilichev
author_sort I. A. Makarov
collection DOAJ
description Some Russian cosmonauts in space flight have revealed swelling of the optic nerve head of varying severity. Four clinical cases presented in this article. A quantitative method for the analysis of OCT images of the optic nerve head and the retina has been developed for the diagnosis and monitoring of the optic nerve’s state. This method is quite informative, regardless of the opinion of each specific medical consultant; diagnosis of optic nerve head edema can be performed according to the generally accepted Frisen’s grading, and thus objectify its diagnostic capabilities. In cases when changes in the optic nerve head are not visualized during ophthalmoscopy, quantitative analysis of OCT images allows one to quantify the presence of optic nerve head edema at the subclinical stage. This objective diagnostic method allows us to establish and quantify the amount of industrial activity, which, with edema of the optic nerve because of intracranial hypertension, mostly pronounced on the nasal side of the nerve disc. Determining the thickness of the retina and head of the optic nerve in the nasal side are paramount for monitoring changes in papilledema in dynamics, especially in the subclinical and 0 stage according to Frisen. Quantitative measurements of the optic nerve head in the temporal side are necessary for the diagnosis, developed papilledema and differential diagnosis of 1-2 stages on the Frisen scale. The use of this diagnostic method has the great importance in assessing the influence of various factors of the space flight on the optic nerve head.
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spelling doaj.art-dcd93eee342a4d4cbd93f31405a7fbe52023-03-13T09:08:41ZrusOphthalmology Publishing GroupOftalʹmologiâ1816-50952500-08452020-12-0117475276010.18008/1816-5095-2020-4-752-760702Papilledema in Space Flight: Pathogenesis, Diagnostics and MonitoringI. A. Makarov0S. N. Danilichev1ФГБУН ГНЦ РФ «Институт медико-биологических проблем» Российской академии наукФГБУН ГНЦ РФ «Институт медико-биологических проблем» Российской академии наук; ФГБУ «Научно-исследовательский испытательный центр подготовки космонавтов имени Ю.А. Гагарина»Some Russian cosmonauts in space flight have revealed swelling of the optic nerve head of varying severity. Four clinical cases presented in this article. A quantitative method for the analysis of OCT images of the optic nerve head and the retina has been developed for the diagnosis and monitoring of the optic nerve’s state. This method is quite informative, regardless of the opinion of each specific medical consultant; diagnosis of optic nerve head edema can be performed according to the generally accepted Frisen’s grading, and thus objectify its diagnostic capabilities. In cases when changes in the optic nerve head are not visualized during ophthalmoscopy, quantitative analysis of OCT images allows one to quantify the presence of optic nerve head edema at the subclinical stage. This objective diagnostic method allows us to establish and quantify the amount of industrial activity, which, with edema of the optic nerve because of intracranial hypertension, mostly pronounced on the nasal side of the nerve disc. Determining the thickness of the retina and head of the optic nerve in the nasal side are paramount for monitoring changes in papilledema in dynamics, especially in the subclinical and 0 stage according to Frisen. Quantitative measurements of the optic nerve head in the temporal side are necessary for the diagnosis, developed papilledema and differential diagnosis of 1-2 stages on the Frisen scale. The use of this diagnostic method has the great importance in assessing the influence of various factors of the space flight on the optic nerve head.https://www.ophthalmojournal.com/opht/article/view/1369sansоктквантитативный анализ изображенийотек зрительного нерва
spellingShingle I. A. Makarov
S. N. Danilichev
Papilledema in Space Flight: Pathogenesis, Diagnostics and Monitoring
Oftalʹmologiâ
sans
окт
квантитативный анализ изображений
отек зрительного нерва
title Papilledema in Space Flight: Pathogenesis, Diagnostics and Monitoring
title_full Papilledema in Space Flight: Pathogenesis, Diagnostics and Monitoring
title_fullStr Papilledema in Space Flight: Pathogenesis, Diagnostics and Monitoring
title_full_unstemmed Papilledema in Space Flight: Pathogenesis, Diagnostics and Monitoring
title_short Papilledema in Space Flight: Pathogenesis, Diagnostics and Monitoring
title_sort papilledema in space flight pathogenesis diagnostics and monitoring
topic sans
окт
квантитативный анализ изображений
отек зрительного нерва
url https://www.ophthalmojournal.com/opht/article/view/1369
work_keys_str_mv AT iamakarov papilledemainspaceflightpathogenesisdiagnosticsandmonitoring
AT sndanilichev papilledemainspaceflightpathogenesisdiagnosticsandmonitoring