LARRPM restricts lung adenocarcinoma progression and M2 macrophage polarization through epigenetically regulating LINC00240 and CSF1

LARRPM restricts lung adenocarcinoma progression and M2 macrophage polarization through epigenetically regulating LINC00240 and CSF1

Abstract Background Long non-coding RNAs (lncRNAs) are critical regulators in lung adenocarcinoma (LUAD). M2-type tumor-associated macrophages (TAMs) also play oncogenic roles in LUAD. However, the involvement of lncRNAs in TAM activation is still largely unknown. Methods The expressions of LARRPM,...

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Bibliographic Details
Main Authors: Yue Li, Chen Chen, Hai-lin Liu, Zhen-fa Zhang, Chang-li Wang
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Cellular & Molecular Biology Letters
Subjects:
Tumor-associated macrophage
Lung adenocarcinoma
Progression
DNA methylation
CSF1
Online Access:https://doi.org/10.1186/s11658-022-00376-y

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