Characterization of a Lytic Bacteriophage and Demonstration of Its Combined Lytic Effect with a K2 Depolymerase on the Hypervirulent <i>Klebsiella pneumoniae</i> Strain 52145

Characterization of a Lytic Bacteriophage and Demonstration of Its Combined Lytic Effect with a K2 Depolymerase on the Hypervirulent <i>Klebsiella pneumoniae</i> Strain 52145

<i>Klebsiella pneumoniae</i> is a nosocomial pathogen. Among its virulence factors is the capsule with a prominent role in defense and biofilm formation. Bacteriophages (phages) can evoke the lysis of bacterial cells. Due to the mode of action of their polysaccharide depolymerase enzymes...

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Bibliographic Details
Main Authors: Botond Zsombor Pertics, Tamás Kovács, György Schneider
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Microorganisms
Subjects:
<i>Klebsiella pneumoniae</i>
Klebsiella phage
bacteriophage
capsule serotype
capsule depoly-merase
phage receptor, K2 serotype
Online Access:https://www.mdpi.com/2076-2607/11/3/669

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