Magnetic Hyperthermia for Cancer Treatment: Main Parameters Affecting the Outcome of In Vitro and In Vivo Studies
Magnetic hyperthermia (MHT) is being investigated as a cancer treatment since the 1950s. Recent advancements in the field of nanotechnology have resulted in a notable increase in the number of MHT studies. Most of these studies explore MHT as a stand-alone treatment or as an adjuvant therapy in a pr...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-06-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/25/12/2874 |
| _version_ | 1827714443360862208 |
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| author | Vânia Vilas-Boas Félix Carvalho Begoña Espiña |
| author_facet | Vânia Vilas-Boas Félix Carvalho Begoña Espiña |
| author_sort | Vânia Vilas-Boas |
| collection | DOAJ |
| description | Magnetic hyperthermia (MHT) is being investigated as a cancer treatment since the 1950s. Recent advancements in the field of nanotechnology have resulted in a notable increase in the number of MHT studies. Most of these studies explore MHT as a stand-alone treatment or as an adjuvant therapy in a preclinical context. However, despite all the scientific effort, only a minority of the MHT-devoted nanomaterials and approaches made it to clinical context. The outcome of an MHT experiment is largely influenced by a number of variables that should be considered when setting up new MHT studies. This review highlights and discusses the main parameters affecting the outcome of preclinical MHT, aiming to provide adequate assistance in the design of new, more efficient MHT studies. |
| first_indexed | 2024-03-10T18:58:45Z |
| format | Article |
| id | doaj.art-dcdd7ddd673f4a06b23b9cc2d29f8f14 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-10T18:58:45Z |
| publishDate | 2020-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-dcdd7ddd673f4a06b23b9cc2d29f8f142023-11-20T04:36:32ZengMDPI AGMolecules1420-30492020-06-012512287410.3390/molecules25122874Magnetic Hyperthermia for Cancer Treatment: Main Parameters Affecting the Outcome of In Vitro and In Vivo StudiesVânia Vilas-Boas0Félix Carvalho1Begoña Espiña2UCIBIO-REQUIMTE, Laboratory of Toxicology, Biological Sciences Department, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira, 228, 4050-313 Porto, PortugalUCIBIO-REQUIMTE, Laboratory of Toxicology, Biological Sciences Department, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira, 228, 4050-313 Porto, PortugalInternational Iberian Nanotechnology Laboratory, Av. Mestre José Veiga, 4715-330 Braga, PortugalMagnetic hyperthermia (MHT) is being investigated as a cancer treatment since the 1950s. Recent advancements in the field of nanotechnology have resulted in a notable increase in the number of MHT studies. Most of these studies explore MHT as a stand-alone treatment or as an adjuvant therapy in a preclinical context. However, despite all the scientific effort, only a minority of the MHT-devoted nanomaterials and approaches made it to clinical context. The outcome of an MHT experiment is largely influenced by a number of variables that should be considered when setting up new MHT studies. This review highlights and discusses the main parameters affecting the outcome of preclinical MHT, aiming to provide adequate assistance in the design of new, more efficient MHT studies.https://www.mdpi.com/1420-3049/25/12/2874magnetic hyperthermiacancer treatmentefficiencyparameters |
| spellingShingle | Vânia Vilas-Boas Félix Carvalho Begoña Espiña Magnetic Hyperthermia for Cancer Treatment: Main Parameters Affecting the Outcome of In Vitro and In Vivo Studies Molecules magnetic hyperthermia cancer treatment efficiency parameters |
| title | Magnetic Hyperthermia for Cancer Treatment: Main Parameters Affecting the Outcome of In Vitro and In Vivo Studies |
| title_full | Magnetic Hyperthermia for Cancer Treatment: Main Parameters Affecting the Outcome of In Vitro and In Vivo Studies |
| title_fullStr | Magnetic Hyperthermia for Cancer Treatment: Main Parameters Affecting the Outcome of In Vitro and In Vivo Studies |
| title_full_unstemmed | Magnetic Hyperthermia for Cancer Treatment: Main Parameters Affecting the Outcome of In Vitro and In Vivo Studies |
| title_short | Magnetic Hyperthermia for Cancer Treatment: Main Parameters Affecting the Outcome of In Vitro and In Vivo Studies |
| title_sort | magnetic hyperthermia for cancer treatment main parameters affecting the outcome of in vitro and in vivo studies |
| topic | magnetic hyperthermia cancer treatment efficiency parameters |
| url | https://www.mdpi.com/1420-3049/25/12/2874 |
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