Insufficient antibody validation challenges oestrogen receptor beta research
A large body of work into the role of oestrogen receptor b (ERb) in breast cancer is contradictory, hindering future progress. Here the authors conduct extensive validation of anti-ERb antibodies , and show that normal and cancerous breast tissue do not express ERb, consistent with RNA-seq data.
Bibliographic Details
| Main Authors: |
Sandra Andersson,
Mårten Sundberg,
Nusa Pristovsek,
Ahmed Ibrahim,
Philip Jonsson,
Borbala Katona,
Carl-Magnus Clausson,
Agata Zieba,
Margareta Ramström,
Ola Söderberg,
Cecilia Williams,
Anna Asplund |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2017-06-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/ncomms15840
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