Clinical Features and Outcomes of COVID-19 Infections at a Teaching Hospital in Kingston, Jamaica
Objective We examined the demographic, clinical characteristics and indicators of poor outcomes among hospitalised adults with COVID-19 infection at the University Hospital of the West Indies, Jamaica. Methods A retrospective medical record review between March 10 and December 31, 2020 was done a...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Trinidad and Tobago Medical Association (T&TMA)
2023-05-01
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| Series: | Caribbean Medical Journal |
| Subjects: | |
| Online Access: | https://www.caribbeanmedicaljournal.org/2023/05/21/clinical-features-and-outcomes-of-covid-19-infections-at-a-teaching-hospital-in-kingston-jamaica/ |
| _version_ | 1797823114349903872 |
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| author | Tamara Thompson Yvonne Dawkins Swane Rowe-Gardener Lisa Chin-Harty Kyaw Kyaw Hoe Trevor S. Ferguson Kelvin Ehikhametalor Kelly Ann Gordon-Johnson Varough Deyde |
| author_facet | Tamara Thompson Yvonne Dawkins Swane Rowe-Gardener Lisa Chin-Harty Kyaw Kyaw Hoe Trevor S. Ferguson Kelvin Ehikhametalor Kelly Ann Gordon-Johnson Varough Deyde |
| author_sort | Tamara Thompson |
| collection | DOAJ |
| description | Objective
We examined the demographic, clinical characteristics and indicators of poor outcomes among hospitalised adults with COVID-19 infection at the University Hospital of the West Indies, Jamaica.
Methods
A retrospective medical record review between March 10 and December 31, 2020 was done and demographic clinical data were collected.
Results
There were 218 males (mean age 59.5 years) and 144 females (mean age 55.7 years). Hypertension, diabetes mellitus, cardiovascular disease, obesity and chronic kidney disease were the most common comorbidities. Cough, shortness of breath, fever and malaise were the most common presenting complaints. Fifty-one per cent of patients were moderately to severely ill on admission; 11% were critically ill; 18% were admitted to the Intensive Care Unit (ICU). Death occurred in 62 (17%) patients (95% CI 13.6-21.4). Among obese participants, there were increased odds of developing respiratory failure (OR 5.2, p < 0.001), acute kidney injury (OR 4.7, p < 0.001), sepsis (OR 2.9, p =0.013) and the need for ICU care (OR 3.7, p < 0.001). Factors independently associated with increased odds of death were age (OR 1.03 per year, p = 0.013) and obesity (OR 2.26, p = 0.017). Mortality also correlated significantly with D-dimer > 1000 ng/mL (OR 2.78; p = 0.03), serum albumin < 40 g/L (OR 3.54; p = 0.03) and serum LDH > 485 U/L OR 1.92, p = 0.11).
Conclusions
Comorbidities were prevalent among COVID-19 cases in this study. Significant correlates of mortality were older age and obesity. Hypoalbuminaemia, elevated D-dimer and serum LDH at admission also portend a poor prognosis. |
| first_indexed | 2024-03-13T10:18:15Z |
| format | Article |
| id | doaj.art-dce05cb81e864e92b736a58f1ccc9d45 |
| institution | Directory Open Access Journal |
| issn | 2664-5599 |
| language | English |
| last_indexed | 2024-03-13T10:18:15Z |
| publishDate | 2023-05-01 |
| publisher | Trinidad and Tobago Medical Association (T&TMA) |
| record_format | Article |
| series | Caribbean Medical Journal |
| spelling | doaj.art-dce05cb81e864e92b736a58f1ccc9d452023-05-21T10:00:37ZengTrinidad and Tobago Medical Association (T&TMA)Caribbean Medical Journal2664-55992023-05-01Clinical Features and Outcomes of COVID-19 Infections at a Teaching Hospital in Kingston, JamaicaTamara Thompson0Yvonne Dawkins1Swane Rowe-Gardener2Lisa Chin-Harty3Kyaw Kyaw Hoe4Trevor S. Ferguson5Kelvin Ehikhametalor6Kelly Ann Gordon-Johnson7Varough Deyde8Department of Medicine, University of The West Indies, Mona Campus, Kingston, JamaicaDepartment of Medicine, University of The West Indies, Mona Campus, Kingston, JamaicaDepartment of Medicine, University of The West Indies, Mona Campus, Kingston, JamaicaDepartment of Medicine, University of The West Indies, Mona Campus, Kingston, JamaicaDepartment of Medicine, University of The West Indies, Mona Campus, Kingston, JamaicaCaribbean Institute for Health Research, The University of the West Indies, Kingston 7, JamaicaDepartment of Surgery, Radiology, Anesthesia and Intensive Care, The University of the West Indies, Mona, Kingston 7, JamaicaCenters for Disease Control and Prevention, Caribbean Regional Office (CDC/CRO)Centers for Disease Control and Prevention, Caribbean Regional Office (CDC/CRO)Objective We examined the demographic, clinical characteristics and indicators of poor outcomes among hospitalised adults with COVID-19 infection at the University Hospital of the West Indies, Jamaica. Methods A retrospective medical record review between March 10 and December 31, 2020 was done and demographic clinical data were collected. Results There were 218 males (mean age 59.5 years) and 144 females (mean age 55.7 years). Hypertension, diabetes mellitus, cardiovascular disease, obesity and chronic kidney disease were the most common comorbidities. Cough, shortness of breath, fever and malaise were the most common presenting complaints. Fifty-one per cent of patients were moderately to severely ill on admission; 11% were critically ill; 18% were admitted to the Intensive Care Unit (ICU). Death occurred in 62 (17%) patients (95% CI 13.6-21.4). Among obese participants, there were increased odds of developing respiratory failure (OR 5.2, p < 0.001), acute kidney injury (OR 4.7, p < 0.001), sepsis (OR 2.9, p =0.013) and the need for ICU care (OR 3.7, p < 0.001). Factors independently associated with increased odds of death were age (OR 1.03 per year, p = 0.013) and obesity (OR 2.26, p = 0.017). Mortality also correlated significantly with D-dimer > 1000 ng/mL (OR 2.78; p = 0.03), serum albumin < 40 g/L (OR 3.54; p = 0.03) and serum LDH > 485 U/L OR 1.92, p = 0.11). Conclusions Comorbidities were prevalent among COVID-19 cases in this study. Significant correlates of mortality were older age and obesity. Hypoalbuminaemia, elevated D-dimer and serum LDH at admission also portend a poor prognosis.https://www.caribbeanmedicaljournal.org/2023/05/21/clinical-features-and-outcomes-of-covid-19-infections-at-a-teaching-hospital-in-kingston-jamaica/sars-cov-2covid-19jamaicaoutcomesmortality |
| spellingShingle | Tamara Thompson Yvonne Dawkins Swane Rowe-Gardener Lisa Chin-Harty Kyaw Kyaw Hoe Trevor S. Ferguson Kelvin Ehikhametalor Kelly Ann Gordon-Johnson Varough Deyde Clinical Features and Outcomes of COVID-19 Infections at a Teaching Hospital in Kingston, Jamaica Caribbean Medical Journal sars-cov-2 covid-19 jamaica outcomes mortality |
| title | Clinical Features and Outcomes of COVID-19 Infections at a Teaching Hospital in Kingston, Jamaica |
| title_full | Clinical Features and Outcomes of COVID-19 Infections at a Teaching Hospital in Kingston, Jamaica |
| title_fullStr | Clinical Features and Outcomes of COVID-19 Infections at a Teaching Hospital in Kingston, Jamaica |
| title_full_unstemmed | Clinical Features and Outcomes of COVID-19 Infections at a Teaching Hospital in Kingston, Jamaica |
| title_short | Clinical Features and Outcomes of COVID-19 Infections at a Teaching Hospital in Kingston, Jamaica |
| title_sort | clinical features and outcomes of covid 19 infections at a teaching hospital in kingston jamaica |
| topic | sars-cov-2 covid-19 jamaica outcomes mortality |
| url | https://www.caribbeanmedicaljournal.org/2023/05/21/clinical-features-and-outcomes-of-covid-19-infections-at-a-teaching-hospital-in-kingston-jamaica/ |
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