Wearable Plasma Pads for Biomedical Applications
A plasma pad that can be attached to human skin was developed for aesthetic and dermatological treatment. A polyimide film was used for the dielectric layer of the flexible pad, and high-voltage and ground electrodes were placed on the film surface. Medical gauze covered the ground electrodes and wa...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2017-12-01
|
| Series: | Applied Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-3417/7/12/1308 |
| _version_ | 1828421223533510656 |
|---|---|
| author | Junggil Kim Kyong-Hoon Choi Yunjung Kim Bong Joo Park Guangsup Cho |
| author_facet | Junggil Kim Kyong-Hoon Choi Yunjung Kim Bong Joo Park Guangsup Cho |
| author_sort | Junggil Kim |
| collection | DOAJ |
| description | A plasma pad that can be attached to human skin was developed for aesthetic and dermatological treatment. A polyimide film was used for the dielectric layer of the flexible pad, and high-voltage and ground electrodes were placed on the film surface. Medical gauze covered the ground electrodes and was placed facing the skin to act as a spacer; thus, the plasma floated between the gauze and ground electrodes. In vitro and in vivo biocompatibility tests of the pad showed no cytotoxicity to normal cells and no irritation of mouse skin. Antibacterial activity was shown against Staphylococcus aureus and clinical isolates of methicillin-resistant S. aureus. Furthermore, skin wound healing with increased hair growth resulting from increased exogenous nitric oxide and capillary tube formation induced by the plasma pad was also confirmed in vivo. The present study suggests that this flexible and wearable plasma pad can be used for biomedical applications such as treatment of wounds and bacterial infections. |
| first_indexed | 2024-12-10T15:26:19Z |
| format | Article |
| id | doaj.art-dce0aa89468c4ae284df2c5e833d8d32 |
| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-12-10T15:26:19Z |
| publishDate | 2017-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Sciences |
| spelling | doaj.art-dce0aa89468c4ae284df2c5e833d8d322022-12-22T01:43:33ZengMDPI AGApplied Sciences2076-34172017-12-01712130810.3390/app7121308app7121308Wearable Plasma Pads for Biomedical ApplicationsJunggil Kim0Kyong-Hoon Choi1Yunjung Kim2Bong Joo Park3Guangsup Cho4Department of Electrical and Biological Physics, Kwangwoon University, 20 Kwangwoon-Ro, Nowon Wallgye, Seoul 01897, KoreaInstitute of Biomaterials, Kwangwoon University, 20 Kwangwoon-Ro, Nowon Wallgye, Seoul 01897, KoreaDepartment of Electrical and Biological Physics, Kwangwoon University, 20 Kwangwoon-Ro, Nowon Wallgye, Seoul 01897, KoreaDepartment of Electrical and Biological Physics, Kwangwoon University, 20 Kwangwoon-Ro, Nowon Wallgye, Seoul 01897, KoreaDepartment of Electrical and Biological Physics, Kwangwoon University, 20 Kwangwoon-Ro, Nowon Wallgye, Seoul 01897, KoreaA plasma pad that can be attached to human skin was developed for aesthetic and dermatological treatment. A polyimide film was used for the dielectric layer of the flexible pad, and high-voltage and ground electrodes were placed on the film surface. Medical gauze covered the ground electrodes and was placed facing the skin to act as a spacer; thus, the plasma floated between the gauze and ground electrodes. In vitro and in vivo biocompatibility tests of the pad showed no cytotoxicity to normal cells and no irritation of mouse skin. Antibacterial activity was shown against Staphylococcus aureus and clinical isolates of methicillin-resistant S. aureus. Furthermore, skin wound healing with increased hair growth resulting from increased exogenous nitric oxide and capillary tube formation induced by the plasma pad was also confirmed in vivo. The present study suggests that this flexible and wearable plasma pad can be used for biomedical applications such as treatment of wounds and bacterial infections.https://www.mdpi.com/2076-3417/7/12/1308biomedicinedielectric barrier dischargeplasma devicesplasma padsplasma treatment |
| spellingShingle | Junggil Kim Kyong-Hoon Choi Yunjung Kim Bong Joo Park Guangsup Cho Wearable Plasma Pads for Biomedical Applications Applied Sciences biomedicine dielectric barrier discharge plasma devices plasma pads plasma treatment |
| title | Wearable Plasma Pads for Biomedical Applications |
| title_full | Wearable Plasma Pads for Biomedical Applications |
| title_fullStr | Wearable Plasma Pads for Biomedical Applications |
| title_full_unstemmed | Wearable Plasma Pads for Biomedical Applications |
| title_short | Wearable Plasma Pads for Biomedical Applications |
| title_sort | wearable plasma pads for biomedical applications |
| topic | biomedicine dielectric barrier discharge plasma devices plasma pads plasma treatment |
| url | https://www.mdpi.com/2076-3417/7/12/1308 |
| work_keys_str_mv | AT junggilkim wearableplasmapadsforbiomedicalapplications AT kyonghoonchoi wearableplasmapadsforbiomedicalapplications AT yunjungkim wearableplasmapadsforbiomedicalapplications AT bongjoopark wearableplasmapadsforbiomedicalapplications AT guangsupcho wearableplasmapadsforbiomedicalapplications |