Short-Time Impedance Spectroscopy Using a Mode-Switching Nonsinusoidal Oscillator: Applicability to Biological Tissues and Continuous Measurement
Herein, we propose an impedance spectroscopy method using a mode-switching nonsinusoidal oscillator and apply this method for measuring the impedance of biological tissues and continuous impedance measurement. To obtain impedance spectra over a wide frequency range, we fabricated a novel nonsinusoid...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-10-01
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| Series: | Sensors |
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| Online Access: | https://www.mdpi.com/1424-8220/21/21/6951 |
| _version_ | 1797511888238542848 |
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| author | Tomiharu Yamaguchi Emiyu Ogawa Akinori Ueno |
| author_facet | Tomiharu Yamaguchi Emiyu Ogawa Akinori Ueno |
| author_sort | Tomiharu Yamaguchi |
| collection | DOAJ |
| description | Herein, we propose an impedance spectroscopy method using a mode-switching nonsinusoidal oscillator and apply this method for measuring the impedance of biological tissues and continuous impedance measurement. To obtain impedance spectra over a wide frequency range, we fabricated a novel nonsinusoidal oscillator incorporating binary counters and analog switches. This oscillator could periodically switch oscillation frequency through the mode switching of the feedback resistor. From the oscillation waveform at each oscillation frequency of this circuit (oscillator), we determined the impedance spectrum of a measured object using the discrete-time Fourier transform. Subsequently, we obtained the broad impedance spectrum of the measured object by merging odd-order harmonic spectral components up to the 19th order for each oscillation frequency. From the measured spectrum, the resistive and capacitive components of the circuit simulating bioimpedance were estimated with high accuracy. Moreover, the proposed method was used to measure the impedance of porcine myocardium; changes in the impedance spectrum of the myocardial tissue due to coagulation could be measured. Furthermore, rapid variations in the resistance value of a CdS photocell could be continuously measured using the proposed method. |
| first_indexed | 2024-03-10T05:53:21Z |
| format | Article |
| id | doaj.art-dce32157d747439a8e195c48adcd00fb |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-03-10T05:53:21Z |
| publishDate | 2021-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-dce32157d747439a8e195c48adcd00fb2023-11-22T21:34:22ZengMDPI AGSensors1424-82202021-10-012121695110.3390/s21216951Short-Time Impedance Spectroscopy Using a Mode-Switching Nonsinusoidal Oscillator: Applicability to Biological Tissues and Continuous MeasurementTomiharu Yamaguchi0Emiyu Ogawa1Akinori Ueno2Department of Electrical and Electronic Engineering, Tokyo Denki University, Tokyo 120-8551, JapanSchool of Allied Health Science, Kitasato University, Kanagawa 252-0373, JapanDepartment of Electrical and Electronic Engineering, Tokyo Denki University, Tokyo 120-8551, JapanHerein, we propose an impedance spectroscopy method using a mode-switching nonsinusoidal oscillator and apply this method for measuring the impedance of biological tissues and continuous impedance measurement. To obtain impedance spectra over a wide frequency range, we fabricated a novel nonsinusoidal oscillator incorporating binary counters and analog switches. This oscillator could periodically switch oscillation frequency through the mode switching of the feedback resistor. From the oscillation waveform at each oscillation frequency of this circuit (oscillator), we determined the impedance spectrum of a measured object using the discrete-time Fourier transform. Subsequently, we obtained the broad impedance spectrum of the measured object by merging odd-order harmonic spectral components up to the 19th order for each oscillation frequency. From the measured spectrum, the resistive and capacitive components of the circuit simulating bioimpedance were estimated with high accuracy. Moreover, the proposed method was used to measure the impedance of porcine myocardium; changes in the impedance spectrum of the myocardial tissue due to coagulation could be measured. Furthermore, rapid variations in the resistance value of a CdS photocell could be continuously measured using the proposed method.https://www.mdpi.com/1424-8220/21/21/6951capacitive couplingimpedance spectroscopynonsinusoidal oscillatorDFTfrequency switchingbiological application |
| spellingShingle | Tomiharu Yamaguchi Emiyu Ogawa Akinori Ueno Short-Time Impedance Spectroscopy Using a Mode-Switching Nonsinusoidal Oscillator: Applicability to Biological Tissues and Continuous Measurement Sensors capacitive coupling impedance spectroscopy nonsinusoidal oscillator DFT frequency switching biological application |
| title | Short-Time Impedance Spectroscopy Using a Mode-Switching Nonsinusoidal Oscillator: Applicability to Biological Tissues and Continuous Measurement |
| title_full | Short-Time Impedance Spectroscopy Using a Mode-Switching Nonsinusoidal Oscillator: Applicability to Biological Tissues and Continuous Measurement |
| title_fullStr | Short-Time Impedance Spectroscopy Using a Mode-Switching Nonsinusoidal Oscillator: Applicability to Biological Tissues and Continuous Measurement |
| title_full_unstemmed | Short-Time Impedance Spectroscopy Using a Mode-Switching Nonsinusoidal Oscillator: Applicability to Biological Tissues and Continuous Measurement |
| title_short | Short-Time Impedance Spectroscopy Using a Mode-Switching Nonsinusoidal Oscillator: Applicability to Biological Tissues and Continuous Measurement |
| title_sort | short time impedance spectroscopy using a mode switching nonsinusoidal oscillator applicability to biological tissues and continuous measurement |
| topic | capacitive coupling impedance spectroscopy nonsinusoidal oscillator DFT frequency switching biological application |
| url | https://www.mdpi.com/1424-8220/21/21/6951 |
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