Differentiation of human induced pluripotent stem cells into functional lung alveolar epithelial cells in 3D dynamic culture

Differentiation of human induced pluripotent stem cells into functional lung alveolar epithelial cells in 3D dynamic culture

Introduction: Understanding lung epithelium cell development from human induced pluripotent stem cells (IPSCs) in vitro can lead to an individualized model for lung engineering, therapy, and drug testing.Method: We developed a protocol to produce lung mature type I pneumocytes using encapsulation of...

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Bibliographic Details
Main Authors: Sarah Alsobaie, Tamador Alsobaie, Amal Alshammary, Sakis Mantalaris
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
lung development
3D culture
IPSCs
bioprocess
dynamic condition
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1173149/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2023.1173149/full

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