Multivalent Aptamer Approach: Designs, Strategies, and Applications
Aptamers are short and single-stranded DNA or RNA molecules with highly programmable structures that give them the ability to interact specifically with a large variety of targets, including proteins, cells, and small molecules. Multivalent aptamers refer to molecular constructs that combine two or...
Main Authors: | Zhong Wang, Xiuying Yang, Nicholas Zhou Lee, Xudong Cao |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-03-01
|
Series: | Micromachines |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-666X/13/3/436 |
Similar Items
-
Multivalent Aptamers: Versatile Tools for Diagnostic and Therapeutic Applications
by: Mariya Vorobyeva, et al.
Published: (2016-11-01) -
Novel multivalent design of a monoclonal antibody improves binding strength to soluble aggregates of amyloid beta
by: Fadi Rofo, et al.
Published: (2021-09-01) -
Improvement of Aptamer Affinity by Dimerization
by: Kazunori Ikebukuro, et al.
Published: (2008-02-01) -
Multivalent Aptamer‐Based Lysosome‐Targeting Chimeras (LYTACs) Platform for Mono‐ or Dual‐Targeted Proteins Degradation on Cell Surface
by: Qiao Duan, et al.
Published: (2024-05-01) -
Rapid detection of tumor cells in serous effusion by multivalent aptamers based on rolling circle amplification
by: XU Jieru, et al.
Published: (2020-12-01)