PD-1 and PD-L1 expression predict regression and prognosis following neoadjuvant radiochemotherapy of oesophageal adenocarcinoma

PD-1 and PD-L1 expression predict regression and prognosis following neoadjuvant radiochemotherapy of oesophageal adenocarcinoma

Background and purpose: PD-1 and PD-L1 are involved in anticancer immunosurveillance, and their expression may be predictive for therapeutic effectiveness of specific antibodies. Their influence on response to neoadjuvant radiochemotherapy (RCT) and prognosis in patients with oesophageal adenocarcin...

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Bibliographic Details
Main Authors: Holger H. Göbel, Luitpold V.R. Distel, Thomas Aigner, Maike J. Büttner-Herold, Gerhard G. Grabenbauer
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:Clinical and Translational Radiation Oncology
Subjects:
Esophageal adenocarcinoma
CD8+
PD-1
PD-L1
Radiochemotherapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2405630822000246

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