A Case of Blistering Eruptions in Systemic Lupus Erythematosus
Cutaneous vesiculobullous lesions have a wide aetiological spectrum ranging from autoimmunity to medications and infections. Systemic Lupus Erythematosus (SLE) is one of most frequent autoimmune diseases with its cutaneous form being very uncommonly encountered. We report a case of Bullous Systemic...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2019-09-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/13155/42338_CE[Ra1]_F(KM)_PF1(TR_PoG_OM)_PN(SL).pdf |
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| author | Sarojini Raman Abhimanyu Grover Prasant Padhan Urmila Senapati |
| author_facet | Sarojini Raman Abhimanyu Grover Prasant Padhan Urmila Senapati |
| author_sort | Sarojini Raman |
| collection | DOAJ |
| description | Cutaneous vesiculobullous lesions have a wide aetiological spectrum ranging from autoimmunity to medications and infections. Systemic Lupus Erythematosus (SLE) is one of most frequent autoimmune diseases with its cutaneous form being very uncommonly encountered. We report a case of Bullous Systemic Lupus Erythematosus (BSLE). Patient presented with fever, arthalgia and widespread blistering eruptions on face, neck and upper chest wall. Skin biopsy revealed subepidermal bulla and Direct Immunofluorescence (DIF) showed deposition of IgG, IgA, IgM, C3, C1q at the dermoepidermal junction. On treatment lesions healed rapidly. So proper clinical acumina is essential for diagnosis and management of such cases excluding the differentials. |
| first_indexed | 2024-04-12T05:31:40Z |
| format | Article |
| id | doaj.art-dcf6f65d51814814872d1c2a69c3f78b |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-04-12T05:31:40Z |
| publishDate | 2019-09-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-dcf6f65d51814814872d1c2a69c3f78b2022-12-22T03:46:04ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2019-09-01139ED04ED0510.7860/JCDR/2019/42338.13155A Case of Blistering Eruptions in Systemic Lupus ErythematosusSarojini Raman0Abhimanyu Grover1Prasant Padhan2Urmila Senapati3Associate Professor, Department of Pathology, KIMS, BBSR, Bhubaneswar, Odisha, India.Postgraduate Resident, Department of Pathology, KIMS, BBSR, Bhubaneswar, Odisha, India.Associate Professor, Department of Pathology, KIMS, PBMH, Bhubaneswar, Odisha, India.Professor and Head, Department of Pathology, KIMS, BBSR, Bhubaneswar, Odisha, India.Cutaneous vesiculobullous lesions have a wide aetiological spectrum ranging from autoimmunity to medications and infections. Systemic Lupus Erythematosus (SLE) is one of most frequent autoimmune diseases with its cutaneous form being very uncommonly encountered. We report a case of Bullous Systemic Lupus Erythematosus (BSLE). Patient presented with fever, arthalgia and widespread blistering eruptions on face, neck and upper chest wall. Skin biopsy revealed subepidermal bulla and Direct Immunofluorescence (DIF) showed deposition of IgG, IgA, IgM, C3, C1q at the dermoepidermal junction. On treatment lesions healed rapidly. So proper clinical acumina is essential for diagnosis and management of such cases excluding the differentials.https://jcdr.net/articles/PDF/13155/42338_CE[Ra1]_F(KM)_PF1(TR_PoG_OM)_PN(SL).pdfautoimmunitydirectfluorescent antibody techniqueskin |
| spellingShingle | Sarojini Raman Abhimanyu Grover Prasant Padhan Urmila Senapati A Case of Blistering Eruptions in Systemic Lupus Erythematosus Journal of Clinical and Diagnostic Research autoimmunity direct fluorescent antibody technique skin |
| title | A Case of Blistering Eruptions in Systemic Lupus Erythematosus |
| title_full | A Case of Blistering Eruptions in Systemic Lupus Erythematosus |
| title_fullStr | A Case of Blistering Eruptions in Systemic Lupus Erythematosus |
| title_full_unstemmed | A Case of Blistering Eruptions in Systemic Lupus Erythematosus |
| title_short | A Case of Blistering Eruptions in Systemic Lupus Erythematosus |
| title_sort | case of blistering eruptions in systemic lupus erythematosus |
| topic | autoimmunity direct fluorescent antibody technique skin |
| url | https://jcdr.net/articles/PDF/13155/42338_CE[Ra1]_F(KM)_PF1(TR_PoG_OM)_PN(SL).pdf |
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