Biological markers of disease activity in inflammatory bowel diseases
Inflammatory bowel diseases (IBD) are chronic intestinal conditions of multifactorial aetiology including genetic susceptibility, immunological impairment, dysbiosis, and environmental factors. The diagnosis is based on both clinical and endoscopic features, wherein histopathological evaluation rema...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Termedia Publishing House
2023-07-01
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| Series: | Gastroenterology Review |
| Subjects: | |
| Online Access: | https://www.termedia.pl/Biological-markers-of-disease-activity-in-inflammatory-bowel-diseases,41,51066,1,1.html |
| _version_ | 1797692357098864640 |
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| author | Edyta Szymanska Sylwia Szymanska Maciej Dadalski Jaroslaw Kierkus |
| author_facet | Edyta Szymanska Sylwia Szymanska Maciej Dadalski Jaroslaw Kierkus |
| author_sort | Edyta Szymanska |
| collection | DOAJ |
| description | Inflammatory bowel diseases (IBD) are chronic intestinal conditions of multifactorial aetiology including genetic susceptibility, immunological impairment, dysbiosis, and environmental factors. The diagnosis is based on both clinical and endoscopic features, wherein histopathological evaluation remains a gold diagnostic standard. However, fast, reliable, and non-invasive biological markers have been used for years for diagnosis as well as for disease activity monitoring. Currently, commonly used faecal calprotectin is the only biomarker approved and recommended by the European Crohn’s and Colitis Organization (ECCO). Nonetheless, other biological markers discriminating between functional and organic bowel conditions have been widely studied. Therefore, the aim of this manuscript was to review new potential biomarkers of inflammation in IBD. The aim of this study was to review currently available biomarkers of intestinal inflammation and increased gut permeability in IBD. |
| first_indexed | 2024-03-12T02:27:26Z |
| format | Article |
| id | doaj.art-dcf9016219844aaa9190fa2b504cfa34 |
| institution | Directory Open Access Journal |
| issn | 1895-5770 1897-4317 |
| language | English |
| last_indexed | 2024-03-12T02:27:26Z |
| publishDate | 2023-07-01 |
| publisher | Termedia Publishing House |
| record_format | Article |
| series | Gastroenterology Review |
| spelling | doaj.art-dcf9016219844aaa9190fa2b504cfa342023-09-05T11:50:44ZengTermedia Publishing HouseGastroenterology Review1895-57701897-43172023-07-0118214114710.5114/pg.2023.12941251066Biological markers of disease activity in inflammatory bowel diseasesEdyta SzymanskaSylwia SzymanskaMaciej DadalskiJaroslaw KierkusInflammatory bowel diseases (IBD) are chronic intestinal conditions of multifactorial aetiology including genetic susceptibility, immunological impairment, dysbiosis, and environmental factors. The diagnosis is based on both clinical and endoscopic features, wherein histopathological evaluation remains a gold diagnostic standard. However, fast, reliable, and non-invasive biological markers have been used for years for diagnosis as well as for disease activity monitoring. Currently, commonly used faecal calprotectin is the only biomarker approved and recommended by the European Crohn’s and Colitis Organization (ECCO). Nonetheless, other biological markers discriminating between functional and organic bowel conditions have been widely studied. Therefore, the aim of this manuscript was to review new potential biomarkers of inflammation in IBD. The aim of this study was to review currently available biomarkers of intestinal inflammation and increased gut permeability in IBD.https://www.termedia.pl/Biological-markers-of-disease-activity-in-inflammatory-bowel-diseases,41,51066,1,1.htmlinflammatory bowel disease biomarkers zonulin faecal calprotectin elafin haptoglobin. |
| spellingShingle | Edyta Szymanska Sylwia Szymanska Maciej Dadalski Jaroslaw Kierkus Biological markers of disease activity in inflammatory bowel diseases Gastroenterology Review inflammatory bowel disease biomarkers zonulin faecal calprotectin elafin haptoglobin. |
| title | Biological markers of disease activity in inflammatory bowel diseases |
| title_full | Biological markers of disease activity in inflammatory bowel diseases |
| title_fullStr | Biological markers of disease activity in inflammatory bowel diseases |
| title_full_unstemmed | Biological markers of disease activity in inflammatory bowel diseases |
| title_short | Biological markers of disease activity in inflammatory bowel diseases |
| title_sort | biological markers of disease activity in inflammatory bowel diseases |
| topic | inflammatory bowel disease biomarkers zonulin faecal calprotectin elafin haptoglobin. |
| url | https://www.termedia.pl/Biological-markers-of-disease-activity-in-inflammatory-bowel-diseases,41,51066,1,1.html |
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