A Prospective Observational Study of the Recurrence Characteristics of Hunner Lesion After Repeated Transurethral Ablation in Patients With Interstitial Cystitis/Bladder Pain Syndrome
Purpose The aim of this study was to investigate the rate and pattern of recurrence for patients with Hunner lesion (HL) type interstitial cystitis/bladder pain syndrome (IC/BPS) after transurethral ablation. Methods This prospective study included 210 patients with HL type IC/BPS. The primary outco...
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| Format: | Article |
| Language: | English |
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Korean Continence Society
2022-09-01
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| Series: | International Neurourology Journal |
| Subjects: | |
| Online Access: | http://einj.org/upload/pdf/inj-2142408-204.pdf |
| _version_ | 1811227248557031424 |
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| author | Kwang Jin Ko Hye Jin Byun Seokhwan Bang Kyu-Sung Lee |
| author_facet | Kwang Jin Ko Hye Jin Byun Seokhwan Bang Kyu-Sung Lee |
| author_sort | Kwang Jin Ko |
| collection | DOAJ |
| description | Purpose The aim of this study was to investigate the rate and pattern of recurrence for patients with Hunner lesion (HL) type interstitial cystitis/bladder pain syndrome (IC/BPS) after transurethral ablation. Methods This prospective study included 210 patients with HL type IC/BPS. The primary outcomes were the recurrence rate according to 3 patterns of recurrence: pattern A (according to the relationship with the previous surgical site), pattern B (according to the bladder zone), and pattern C (according to the number of lesions). The secondary outcomes were recurrencefree time after treatment according to pattern A and pattern C. Results The pattern A recurrence rate was 50.8% in the same site (A1), 6.7% at a new site (A2), and 42.5% at mixed sites (A3). The pattern B recurrence rate was 10.5% for the anterior wall, 59.0% for the posterior wall, 69.5% for the lateral wall, and 69.0% for the dome area. Multiple lesions recurred as multiple lesions in 75.8% of cases. The pattern C recurrence rate was 10.8% for C1 (single → single), 6.7% for C2 (single → multiple), 6.7% for C3 (multiple → single), and 75.8% for C4 (multiple → multiple). The recurrence-free time in pattern A was 13 months for A1, 12.5 months for A2, and 8 months for A3, with a significant difference between A1 and A3 (P=0.008). There was no significant difference in recurrence-free time in pattern C, either with single or multiple HLs. Conclusions The distinct recurrence characteristics of HLs was not predictable despite repeated ablations. Complete remission should not be expected because the whole bladder was to have the potential to develop the HLs even after repeated transurethral ablation. |
| first_indexed | 2024-04-12T09:39:25Z |
| format | Article |
| id | doaj.art-dcf9553a8bb2482a92ae9d3ef3ae729c |
| institution | Directory Open Access Journal |
| issn | 2093-4777 2093-6931 |
| language | English |
| last_indexed | 2024-04-12T09:39:25Z |
| publishDate | 2022-09-01 |
| publisher | Korean Continence Society |
| record_format | Article |
| series | International Neurourology Journal |
| spelling | doaj.art-dcf9553a8bb2482a92ae9d3ef3ae729c2022-12-22T03:38:09ZengKorean Continence SocietyInternational Neurourology Journal2093-47772093-69312022-09-0126323423810.5213/inj.2142408.204996A Prospective Observational Study of the Recurrence Characteristics of Hunner Lesion After Repeated Transurethral Ablation in Patients With Interstitial Cystitis/Bladder Pain SyndromeKwang Jin Ko0Hye Jin Byun1Seokhwan Bang2Kyu-Sung Lee3 Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea Department of Urology, Keimyung University Dongsan Medical Center, Keimyung University School of Medicine, Daegu, Korea Department of Urology, Seoul St. Mary's Hospital, College of Medicine, Catholic University of Korea, Seoul, Korea Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, KoreaPurpose The aim of this study was to investigate the rate and pattern of recurrence for patients with Hunner lesion (HL) type interstitial cystitis/bladder pain syndrome (IC/BPS) after transurethral ablation. Methods This prospective study included 210 patients with HL type IC/BPS. The primary outcomes were the recurrence rate according to 3 patterns of recurrence: pattern A (according to the relationship with the previous surgical site), pattern B (according to the bladder zone), and pattern C (according to the number of lesions). The secondary outcomes were recurrencefree time after treatment according to pattern A and pattern C. Results The pattern A recurrence rate was 50.8% in the same site (A1), 6.7% at a new site (A2), and 42.5% at mixed sites (A3). The pattern B recurrence rate was 10.5% for the anterior wall, 59.0% for the posterior wall, 69.5% for the lateral wall, and 69.0% for the dome area. Multiple lesions recurred as multiple lesions in 75.8% of cases. The pattern C recurrence rate was 10.8% for C1 (single → single), 6.7% for C2 (single → multiple), 6.7% for C3 (multiple → single), and 75.8% for C4 (multiple → multiple). The recurrence-free time in pattern A was 13 months for A1, 12.5 months for A2, and 8 months for A3, with a significant difference between A1 and A3 (P=0.008). There was no significant difference in recurrence-free time in pattern C, either with single or multiple HLs. Conclusions The distinct recurrence characteristics of HLs was not predictable despite repeated ablations. Complete remission should not be expected because the whole bladder was to have the potential to develop the HLs even after repeated transurethral ablation.http://einj.org/upload/pdf/inj-2142408-204.pdfablationinterstitial cystitisrecurrencetherapeutics |
| spellingShingle | Kwang Jin Ko Hye Jin Byun Seokhwan Bang Kyu-Sung Lee A Prospective Observational Study of the Recurrence Characteristics of Hunner Lesion After Repeated Transurethral Ablation in Patients With Interstitial Cystitis/Bladder Pain Syndrome International Neurourology Journal ablation interstitial cystitis recurrence therapeutics |
| title | A Prospective Observational Study of the Recurrence Characteristics of Hunner Lesion After Repeated Transurethral Ablation in Patients With Interstitial Cystitis/Bladder Pain Syndrome |
| title_full | A Prospective Observational Study of the Recurrence Characteristics of Hunner Lesion After Repeated Transurethral Ablation in Patients With Interstitial Cystitis/Bladder Pain Syndrome |
| title_fullStr | A Prospective Observational Study of the Recurrence Characteristics of Hunner Lesion After Repeated Transurethral Ablation in Patients With Interstitial Cystitis/Bladder Pain Syndrome |
| title_full_unstemmed | A Prospective Observational Study of the Recurrence Characteristics of Hunner Lesion After Repeated Transurethral Ablation in Patients With Interstitial Cystitis/Bladder Pain Syndrome |
| title_short | A Prospective Observational Study of the Recurrence Characteristics of Hunner Lesion After Repeated Transurethral Ablation in Patients With Interstitial Cystitis/Bladder Pain Syndrome |
| title_sort | prospective observational study of the recurrence characteristics of hunner lesion after repeated transurethral ablation in patients with interstitial cystitis bladder pain syndrome |
| topic | ablation interstitial cystitis recurrence therapeutics |
| url | http://einj.org/upload/pdf/inj-2142408-204.pdf |
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