Pseudomonas aeruginosa necrotizing bronchopneumonia
Extremely low birth weight (ELBW) infants are at particularly high risk for infection due to an immature immune system, invasive procedures such as endotracheal intubation, intravascular catheterization, and other factors. Neonatal infections in this population are associated with a high mortality,...
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Format: | Article |
Language: | English |
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University of São Paulo
2021-08-01
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Series: | Autopsy and Case Reports |
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Online Access: | https://www.revistas.usp.br/autopsy/article/view/189942 |
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author | Ranjit I Kylat |
author_facet | Ranjit I Kylat |
author_sort | Ranjit I Kylat |
collection | DOAJ |
description | Extremely low birth weight (ELBW) infants are at particularly high risk for infection due to an immature immune system, invasive procedures such as endotracheal intubation, intravascular catheterization, and other factors. Neonatal infections in this population are associated with a high mortality, poor growth, and neurodevelopmental outcomes. Pseudomonas aeruginosa (P. aeruginosa) infection is an uncommon but potentially devastating cause of pneumonia and sepsis in the ELBW population. P. aeruginosa is an important cause of healthcare-associated infections (HAI) or nosocomial infections. P. aeruginosa can perceive unfavorable environmental changes and orchestrate adaptations by developing plasmid-mediated and adaptive resistance to antibiotics. We describe an ELBW infant born at 26 weeks’ gestation who succumbed at 13 days of life to P. aeruginosa infection. Some of the factors related to the pathogenesis and multidrug resistance are described. |
first_indexed | 2024-12-24T04:14:40Z |
format | Article |
id | doaj.art-dcf95e43a937493c89c4c0428d50e46b |
institution | Directory Open Access Journal |
issn | 2236-1960 |
language | English |
last_indexed | 2024-12-24T04:14:40Z |
publishDate | 2021-08-01 |
publisher | University of São Paulo |
record_format | Article |
series | Autopsy and Case Reports |
spelling | doaj.art-dcf95e43a937493c89c4c0428d50e46b2022-12-21T17:15:59ZengUniversity of São PauloAutopsy and Case Reports2236-19602021-08-0111Pseudomonas aeruginosa necrotizing bronchopneumoniaRanjit I Kylat0University of Arizona, College of Medicine, Department of Pediatrics, Tucson, Arizona, USAExtremely low birth weight (ELBW) infants are at particularly high risk for infection due to an immature immune system, invasive procedures such as endotracheal intubation, intravascular catheterization, and other factors. Neonatal infections in this population are associated with a high mortality, poor growth, and neurodevelopmental outcomes. Pseudomonas aeruginosa (P. aeruginosa) infection is an uncommon but potentially devastating cause of pneumonia and sepsis in the ELBW population. P. aeruginosa is an important cause of healthcare-associated infections (HAI) or nosocomial infections. P. aeruginosa can perceive unfavorable environmental changes and orchestrate adaptations by developing plasmid-mediated and adaptive resistance to antibiotics. We describe an ELBW infant born at 26 weeks’ gestation who succumbed at 13 days of life to P. aeruginosa infection. Some of the factors related to the pathogenesis and multidrug resistance are described.https://www.revistas.usp.br/autopsy/article/view/189942Pseudomonas aeruginosaBronchopneumoniaInfantPrematureLow Birth WeightNeonatal Sepsis |
spellingShingle | Ranjit I Kylat Pseudomonas aeruginosa necrotizing bronchopneumonia Autopsy and Case Reports Pseudomonas aeruginosa Bronchopneumonia Infant Premature Low Birth Weight Neonatal Sepsis |
title | Pseudomonas aeruginosa necrotizing bronchopneumonia |
title_full | Pseudomonas aeruginosa necrotizing bronchopneumonia |
title_fullStr | Pseudomonas aeruginosa necrotizing bronchopneumonia |
title_full_unstemmed | Pseudomonas aeruginosa necrotizing bronchopneumonia |
title_short | Pseudomonas aeruginosa necrotizing bronchopneumonia |
title_sort | pseudomonas aeruginosa necrotizing bronchopneumonia |
topic | Pseudomonas aeruginosa Bronchopneumonia Infant Premature Low Birth Weight Neonatal Sepsis |
url | https://www.revistas.usp.br/autopsy/article/view/189942 |
work_keys_str_mv | AT ranjitikylat pseudomonasaeruginosanecrotizingbronchopneumonia |