METABOLIC AND AUTOIMMUNE RISK FACTORS FOR CORONARY ARTERY DISEASE (CAD) IN HEART TRANSPLANT RECIPIENTS

One of the most essential autoimmunity risk factors for development of CAD are increasing level of anticardiolipin antibodies and homocystein. This report presents retrospective analyses of 39 heart transplant recipients with maximal follow up over 16 years. Our results showed that hyperhomocystenem...

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Main Authors: T. A. Khalilulin, O. V. Orlova, B. L. Mironkov, V. V. Chestuhin, E. N. Kazakov, A. J. Kormer, О. P. Shevchenko
Format: Article
Language:Russian
Published: Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov 2010-06-01
Series:Вестник трансплантологии и искусственных органов
Subjects:
Online Access:https://journal.transpl.ru/vtio/article/view/284
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author T. A. Khalilulin
O. V. Orlova
B. L. Mironkov
V. V. Chestuhin
E. N. Kazakov
A. J. Kormer
О. P. Shevchenko
author_facet T. A. Khalilulin
O. V. Orlova
B. L. Mironkov
V. V. Chestuhin
E. N. Kazakov
A. J. Kormer
О. P. Shevchenko
author_sort T. A. Khalilulin
collection DOAJ
description One of the most essential autoimmunity risk factors for development of CAD are increasing level of anticardiolipin antibodies and homocystein. This report presents retrospective analyses of 39 heart transplant recipients with maximal follow up over 16 years. Our results showed that hyperhomocystenemia and high levels of anticardiolipin antibodies play great value in development of CAD. Thus relative risks for development of CAD in presence both high levels of anticardiolipin antibodies and homocysteine are higher, than in traditional nonimmune risk factors.
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spelling doaj.art-dcf99f22841f4eea95863db8648e18e52025-03-05T14:11:46ZrusFederal Research Center of Transplantology and Artificial Organs named after V.I.ShumakovВестник трансплантологии и искусственных органов1995-11912010-06-01121172010.15825/1995-1191-2010-1-17-20227METABOLIC AND AUTOIMMUNE RISK FACTORS FOR CORONARY ARTERY DISEASE (CAD) IN HEART TRANSPLANT RECIPIENTST. A. Khalilulin0O. V. Orlova1B. L. Mironkov2V. V. Chestuhin3E. N. Kazakov4A. J. Kormer5О. P. Shevchenko6Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowOne of the most essential autoimmunity risk factors for development of CAD are increasing level of anticardiolipin antibodies and homocystein. This report presents retrospective analyses of 39 heart transplant recipients with maximal follow up over 16 years. Our results showed that hyperhomocystenemia and high levels of anticardiolipin antibodies play great value in development of CAD. Thus relative risks for development of CAD in presence both high levels of anticardiolipin antibodies and homocysteine are higher, than in traditional nonimmune risk factors.https://journal.transpl.ru/vtio/article/view/284heart transplantationanticardiolipin antibodieshomocysteineheart transplant coronary artery disease
spellingShingle T. A. Khalilulin
O. V. Orlova
B. L. Mironkov
V. V. Chestuhin
E. N. Kazakov
A. J. Kormer
О. P. Shevchenko
METABOLIC AND AUTOIMMUNE RISK FACTORS FOR CORONARY ARTERY DISEASE (CAD) IN HEART TRANSPLANT RECIPIENTS
Вестник трансплантологии и искусственных органов
heart transplantation
anticardiolipin antibodies
homocysteine
heart transplant coronary artery disease
title METABOLIC AND AUTOIMMUNE RISK FACTORS FOR CORONARY ARTERY DISEASE (CAD) IN HEART TRANSPLANT RECIPIENTS
title_full METABOLIC AND AUTOIMMUNE RISK FACTORS FOR CORONARY ARTERY DISEASE (CAD) IN HEART TRANSPLANT RECIPIENTS
title_fullStr METABOLIC AND AUTOIMMUNE RISK FACTORS FOR CORONARY ARTERY DISEASE (CAD) IN HEART TRANSPLANT RECIPIENTS
title_full_unstemmed METABOLIC AND AUTOIMMUNE RISK FACTORS FOR CORONARY ARTERY DISEASE (CAD) IN HEART TRANSPLANT RECIPIENTS
title_short METABOLIC AND AUTOIMMUNE RISK FACTORS FOR CORONARY ARTERY DISEASE (CAD) IN HEART TRANSPLANT RECIPIENTS
title_sort metabolic and autoimmune risk factors for coronary artery disease cad in heart transplant recipients
topic heart transplantation
anticardiolipin antibodies
homocysteine
heart transplant coronary artery disease
url https://journal.transpl.ru/vtio/article/view/284
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AT vvchestuhin metabolicandautoimmuneriskfactorsforcoronaryarterydiseasecadinhearttransplantrecipients
AT enkazakov metabolicandautoimmuneriskfactorsforcoronaryarterydiseasecadinhearttransplantrecipients
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