Atypical psychopathology and clinical challenges in treating a patient with HIV-associated neurocognitive disorder
Human immunodeficiency virus (HIV) has been known to be associated with primary central nervous system (CNS) manifestations in form of cognitive, behavioral, and affective symptoms. In the absence of opportunistic infections, the initial diagnosis of HAND (HIV-associated neurocognitive disorder) is...
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| Format: | Article |
| Language: | English |
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Termedia Publishing House
2018-09-01
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| Series: | HIV & AIDS Review. International Journal of HIV-Related Problems |
| Subjects: | |
| Online Access: | https://www.termedia.pl/Atypical-psychopathology-and-clinical-challenges-in-treating-a-patient-with-r-nHIV-associated-neurocognitive-disorder,106,33837,1,1.html |
| _version_ | 1818055391562432512 |
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| author | Balaswamy Reddy G Guruprasad Srinivas |
| author_facet | Balaswamy Reddy G Guruprasad Srinivas |
| author_sort | Balaswamy Reddy G |
| collection | DOAJ |
| description | Human immunodeficiency virus (HIV) has been known to be associated with primary central nervous system (CNS) manifestations in form of cognitive, behavioral, and affective symptoms. In the absence of opportunistic infections, the initial diagnosis of HAND (HIV-associated neurocognitive disorder) is difficult to suspect based on above in middle-aged adults, which commonly is misinterpreted as part of psychiatric disorders. Once HIV is diagnosed on serological testing, the personality changes are often colored by cognitive deficits induced by the illness itself, or because of antiretroviral treatment (ART) induced adverse effects, which can interfere with treatment compliance and worsening of HIV status. Acute onset alteration in mental status is known to happen with ART and HIV. With HIV, it can occur either because of primary CNS infection or opportunistic infections, whereas particular medications of ART were known to cause neuro-psychiatric manifestations ranging from anxiety, sleep disturbances, and short-lived increased dreams to psychosis. However, switching into aberrant states of consciousness with intense perceptual alterations for prolonged periods has rarely been reported. This case report highlights the importance of unique psychopathology and clinical helplessness in case of HAND, where cost-benefit of treatment change and psychoeducation of the family was a challenge. |
| first_indexed | 2024-12-10T12:12:12Z |
| format | Article |
| id | doaj.art-dcf9b614792e460c8cbc8e480b8fe4f6 |
| institution | Directory Open Access Journal |
| issn | 1730-1270 1732-2707 |
| language | English |
| last_indexed | 2024-12-10T12:12:12Z |
| publishDate | 2018-09-01 |
| publisher | Termedia Publishing House |
| record_format | Article |
| series | HIV & AIDS Review. International Journal of HIV-Related Problems |
| spelling | doaj.art-dcf9b614792e460c8cbc8e480b8fe4f62022-12-22T01:49:20ZengTermedia Publishing HouseHIV & AIDS Review. International Journal of HIV-Related Problems1730-12701732-27072018-09-0117322422610.5114/hivar.2018.7849633837Atypical psychopathology and clinical challenges in treating a patient with HIV-associated neurocognitive disorderBalaswamy Reddy GGuruprasad SrinivasHuman immunodeficiency virus (HIV) has been known to be associated with primary central nervous system (CNS) manifestations in form of cognitive, behavioral, and affective symptoms. In the absence of opportunistic infections, the initial diagnosis of HAND (HIV-associated neurocognitive disorder) is difficult to suspect based on above in middle-aged adults, which commonly is misinterpreted as part of psychiatric disorders. Once HIV is diagnosed on serological testing, the personality changes are often colored by cognitive deficits induced by the illness itself, or because of antiretroviral treatment (ART) induced adverse effects, which can interfere with treatment compliance and worsening of HIV status. Acute onset alteration in mental status is known to happen with ART and HIV. With HIV, it can occur either because of primary CNS infection or opportunistic infections, whereas particular medications of ART were known to cause neuro-psychiatric manifestations ranging from anxiety, sleep disturbances, and short-lived increased dreams to psychosis. However, switching into aberrant states of consciousness with intense perceptual alterations for prolonged periods has rarely been reported. This case report highlights the importance of unique psychopathology and clinical helplessness in case of HAND, where cost-benefit of treatment change and psychoeducation of the family was a challenge.https://www.termedia.pl/Atypical-psychopathology-and-clinical-challenges-in-treating-a-patient-with-r-nHIV-associated-neurocognitive-disorder,106,33837,1,1.htmlHIV neurocognitive atypical |
| spellingShingle | Balaswamy Reddy G Guruprasad Srinivas Atypical psychopathology and clinical challenges in treating a patient with HIV-associated neurocognitive disorder HIV & AIDS Review. International Journal of HIV-Related Problems HIV neurocognitive atypical |
| title | Atypical psychopathology and clinical challenges in treating a patient with
HIV-associated neurocognitive disorder |
| title_full | Atypical psychopathology and clinical challenges in treating a patient with
HIV-associated neurocognitive disorder |
| title_fullStr | Atypical psychopathology and clinical challenges in treating a patient with
HIV-associated neurocognitive disorder |
| title_full_unstemmed | Atypical psychopathology and clinical challenges in treating a patient with
HIV-associated neurocognitive disorder |
| title_short | Atypical psychopathology and clinical challenges in treating a patient with
HIV-associated neurocognitive disorder |
| title_sort | atypical psychopathology and clinical challenges in treating a patient with hiv associated neurocognitive disorder |
| topic | HIV neurocognitive atypical |
| url | https://www.termedia.pl/Atypical-psychopathology-and-clinical-challenges-in-treating-a-patient-with-r-nHIV-associated-neurocognitive-disorder,106,33837,1,1.html |
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