Nodular hidradenoma mimicking nodular basal cell carcinoma
A 40-year-old woman, phototype III, presented with an erythematous, sessile nodule with small ulceration points on the right forearm for 1 year and 6 months. Dermoscopy showed structures similar to blue-gray globules, arboriform telangiectasias with some thickened vessels, bright white spots, and mi...
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| Format: | Article |
| Language: | English |
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Sociedade Portuguesa de Dermatologia e Venereologia
2023-01-01
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| Series: | Revista da Sociedade Portuguesa de Dermatologia e Venereologia |
| Subjects: | |
| Online Access: | https://www.portuguesejournalofdermatology.com/frame_esp.php?id=76 |
| _version_ | 1797853149856268288 |
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| author | Elisangela M.A. Lima Mariana O. Fernandes Marina Silva Flávia R. Ferreira Fernanda G. Moya |
| author_facet | Elisangela M.A. Lima Mariana O. Fernandes Marina Silva Flávia R. Ferreira Fernanda G. Moya |
| author_sort | Elisangela M.A. Lima |
| collection | DOAJ |
| description | A 40-year-old woman, phototype III, presented with an erythematous, sessile nodule with small ulceration points on the right forearm for 1 year and 6 months. Dermoscopy showed structures similar to blue-gray globules, arboriform telangiectasias with some thickened vessels, bright white spots, and microulceration points. The main hypothesis of nodular basal cell carcinoma (BCC) and excisional biopsy of the lesion were performed. Histopathology showed nodular adnexal epithelial neoplasia without atypia, with a focal connection to the epidermis, a clear cell component, and immunohistochemistry positivity for p63, epithelial membrane antigen (EMA), and cytokeratin AE1/AE3, concluding the diagnosis of nodular hidradenoma. The unusual presentation, mimicking a nodular BCC, and the importance of the correct approach to atypical lesions motivated this report.
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| first_indexed | 2024-04-09T19:45:55Z |
| format | Article |
| id | doaj.art-dd006738d7434ffdad46c21885649f9c |
| institution | Directory Open Access Journal |
| issn | 2182-2395 2182-2409 |
| language | English |
| last_indexed | 2024-04-09T19:45:55Z |
| publishDate | 2023-01-01 |
| publisher | Sociedade Portuguesa de Dermatologia e Venereologia |
| record_format | Article |
| series | Revista da Sociedade Portuguesa de Dermatologia e Venereologia |
| spelling | doaj.art-dd006738d7434ffdad46c21885649f9c2023-04-03T20:24:27ZengSociedade Portuguesa de Dermatologia e VenereologiaRevista da Sociedade Portuguesa de Dermatologia e Venereologia2182-23952182-24092023-01-0181110.24875/PJDV.22000024Nodular hidradenoma mimicking nodular basal cell carcinomaElisangela M.A. Lima0Mariana O. Fernandes1Marina Silva2Flávia R. Ferreira3Fernanda G. Moya4Department of Dermatology, Hospital Municipal Universitário de Taubaté (H.MUT/UNITAU); Department of Dermatology, Departamento de Medicina da Universidade de Taubaté, UNITAU; São Paulo, BrasilDepartment of Dermatology, Hospital Municipal Universitário de Taubaté (H.MUT/UNITAU), São Paulo, Brasil.Department of Dermatology, Hospital Municipal Universitário de Taubaté (H.MUT/UNITAU), São Paulo, BrasilDepartment of Dermatology, Hospital Municipal Universitário de Taubaté (H.MUT/UNITAU); Department of Dermatology, Departamento de Medicina da Universidade de Taubaté, UNITAU; São Paulo, BrasilDepartment of Pathological Anatomy, Hospital do Servidor Público Estadual de São Paulo. São Paulo, BrasilA 40-year-old woman, phototype III, presented with an erythematous, sessile nodule with small ulceration points on the right forearm for 1 year and 6 months. Dermoscopy showed structures similar to blue-gray globules, arboriform telangiectasias with some thickened vessels, bright white spots, and microulceration points. The main hypothesis of nodular basal cell carcinoma (BCC) and excisional biopsy of the lesion were performed. Histopathology showed nodular adnexal epithelial neoplasia without atypia, with a focal connection to the epidermis, a clear cell component, and immunohistochemistry positivity for p63, epithelial membrane antigen (EMA), and cytokeratin AE1/AE3, concluding the diagnosis of nodular hidradenoma. The unusual presentation, mimicking a nodular BCC, and the importance of the correct approach to atypical lesions motivated this report. https://www.portuguesejournalofdermatology.com/frame_esp.php?id=76Acrospiroma. Basal cell Carcinoma. Dermoscopy. Histology. Immunohistochemistry. |
| spellingShingle | Elisangela M.A. Lima Mariana O. Fernandes Marina Silva Flávia R. Ferreira Fernanda G. Moya Nodular hidradenoma mimicking nodular basal cell carcinoma Revista da Sociedade Portuguesa de Dermatologia e Venereologia Acrospiroma. Basal cell Carcinoma. Dermoscopy. Histology. Immunohistochemistry. |
| title | Nodular hidradenoma mimicking nodular basal cell carcinoma |
| title_full | Nodular hidradenoma mimicking nodular basal cell carcinoma |
| title_fullStr | Nodular hidradenoma mimicking nodular basal cell carcinoma |
| title_full_unstemmed | Nodular hidradenoma mimicking nodular basal cell carcinoma |
| title_short | Nodular hidradenoma mimicking nodular basal cell carcinoma |
| title_sort | nodular hidradenoma mimicking nodular basal cell carcinoma |
| topic | Acrospiroma. Basal cell Carcinoma. Dermoscopy. Histology. Immunohistochemistry. |
| url | https://www.portuguesejournalofdermatology.com/frame_esp.php?id=76 |
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