Late-rising CD4 T cells resolve mouse cytomegalovirus persistent replication in the salivary gland.

Conventional antiviral memory CD4 T cells typically arise during the first two weeks of acute infection. Unlike most viruses, cytomegalovirus (CMV) exhibits an extended persistent replication phase followed by lifelong latency accompanied with some gene expression. We show that during mouse CMV (MCM...

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Bibliographic Details
Main Authors: Simon Brunel, Gaelle Picarda, Ankan Gupta, Raima Ghosh, Bryan McDonald, Rachid El Morabiti, Wenjin Jiang, Jason A Greenbaum, Barbara Adler, Gregory Seumois, Michael Croft, Pandurangan Vijayanand, Chris A Benedict
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011852&type=printable