Nuclear Syndecan-1 Regulates Epithelial-Mesenchymal Plasticity in Tumor Cells

Nuclear Syndecan-1 Regulates Epithelial-Mesenchymal Plasticity in Tumor Cells

Tumor cells undergoing epithelial-mesenchymal transition (EMT) lose cell surface adhesion molecules and gain invasive and metastatic properties. EMT is a plastic process and tumor cells may shift between different epithelial-mesenchymal states during metastasis. However, how this is regulated is not...

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Bibliographic Details
Main Authors: Ashish Kumar-Singh, Malgorzata Maria Parniewska, Nikolina Giotopoulou, Joman Javadi, Wenwen Sun, Tünde Szatmári, Katalin Dobra, Anders Hjerpe, Jonas Fuxe
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Biology
Subjects:
syndecan-1
SDC1
nuclear translocation
epithelial-mesenchymal transition
plasticity
TGF-β1
Online Access:https://www.mdpi.com/2079-7737/10/6/521

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