An imbalance between specialized pro-resolving lipid mediators and pro-inflammatory leukotrienes promotes instability of atherosclerotic plaques
Atherosclerosis progression is linked to inflammatory processes in the blood vessel wall. Here, the authors show that, with the progression of atherosclerosis, the resolution of inflammation is impaired as the result of an imbalance between specialized pro-resolving lipid mediators and leukotrienes.
Bibliographic Details
| Main Authors: |
Gabrielle Fredman,
Jason Hellmann,
Jonathan D. Proto,
George Kuriakose,
Romain A. Colas,
Bernhard Dorweiler,
E. Sander Connolly,
Robert Solomon,
David M. Jones,
Eric J. Heyer,
Matthew Spite,
Ira Tabas |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2016-09-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/ncomms12859
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