Dexmedetomidine Pre-Treatment of Neonatal Rats Prevents Sevoflurane-Induced Deficits in Learning and Memory in the Adult Animals

Dexmedetomidine Pre-Treatment of Neonatal Rats Prevents Sevoflurane-Induced Deficits in Learning and Memory in the Adult Animals

Anesthetics have been shown to cause cytotoxicity, cell death, affect neuronal growth and connectivity in animal models; however, their effects on learning and memory remain to be fully defined. Here, we examined the effects of the inhalation anesthetic sevoflurane (SEV)—both in vivo by examining le...

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Bibliographic Details
Main Authors: Nerea Jimenez-Tellez, Marcus Pehar, Fahad Iqbal, Alberto Casas-Ortiz, Tiffany Rice, Naweed I. Syed
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Biomedicines
Subjects:
sevoflurane
dexmedetomidine
anesthetics
learning and memory
mitochondria
Online Access:https://www.mdpi.com/2227-9059/11/2/391

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