CARDIAC LESION IN CHURG - STRAUSS SYNDROME

Cardiac involvement is the most important prognostic factor in eosinophilic granulomatosis with polyangiitis (Churg - Strauss syndrome). We report a case of Churg - Strauss syndrome in 65-year-old women masquerading as a non-ST elevation myocardial infarction. She had chest discomfort, dyspnea and S...

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Main Authors: E. S. Eniseeva, G. P. Gurtovaya, O. V. Kanya, A. A. Stefanenkova
Format: Article
Language:Russian
Published: Scientific Сentre for Family Health and Human Reproduction Problems 2016-11-01
Series:Acta Biomedica Scientifica
Subjects:
Online Access:https://www.actabiomedica.ru/jour/article/view/349
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author E. S. Eniseeva
G. P. Gurtovaya
O. V. Kanya
A. A. Stefanenkova
author_facet E. S. Eniseeva
G. P. Gurtovaya
O. V. Kanya
A. A. Stefanenkova
author_sort E. S. Eniseeva
collection DOAJ
description Cardiac involvement is the most important prognostic factor in eosinophilic granulomatosis with polyangiitis (Churg - Strauss syndrome). We report a case of Churg - Strauss syndrome in 65-year-old women masquerading as a non-ST elevation myocardial infarction. She had chest discomfort, dyspnea and ST depression, high troponin level and so myocardial infarction was diagnosed. She had had asthma for 4 years but had no eosinophilia in peripheral blood and lesions in the lungs at the time of the first hospitalization. Her skin was clean without rashes. 3 months later she was hospitalized again having pulmonary infiltrates. Laboratory tests revealed that eosinophil was significantly increased. Cardiac involvement in a pathological process led to death. Histological examination of heart and lungs showed necrotic coronary vasculitis, granulomas and perivascular eosinophilic infiltrates in myocardium, endocardium, pericardium and pulmonary eosinophilic infiltrates.
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spelling doaj.art-dd0aa70306774e948c462686d04155b22024-03-28T07:49:17ZrusScientific Сentre for Family Health and Human Reproduction ProblemsActa Biomedica Scientifica2541-94202587-95962016-11-011621021310.12737/23843349CARDIAC LESION IN CHURG - STRAUSS SYNDROMEE. S. Eniseeva0G. P. Gurtovaya1O. V. Kanya2A. A. Stefanenkova3ГБОУ ДПО «Иркутская государственная медицинская академия последипломного образования» Минздрава РоссииФГБОУ ВО «Иркутский государственный медицинский университет» Минздрава РоссииГБУЗ Иркутское областное патологоанатомическое бюроГБУЗ Иркутское областное патологоанатомическое бюроCardiac involvement is the most important prognostic factor in eosinophilic granulomatosis with polyangiitis (Churg - Strauss syndrome). We report a case of Churg - Strauss syndrome in 65-year-old women masquerading as a non-ST elevation myocardial infarction. She had chest discomfort, dyspnea and ST depression, high troponin level and so myocardial infarction was diagnosed. She had had asthma for 4 years but had no eosinophilia in peripheral blood and lesions in the lungs at the time of the first hospitalization. Her skin was clean without rashes. 3 months later she was hospitalized again having pulmonary infiltrates. Laboratory tests revealed that eosinophil was significantly increased. Cardiac involvement in a pathological process led to death. Histological examination of heart and lungs showed necrotic coronary vasculitis, granulomas and perivascular eosinophilic infiltrates in myocardium, endocardium, pericardium and pulmonary eosinophilic infiltrates.https://www.actabiomedica.ru/jour/article/view/349churg - strauss syndromehypereosinophiliacoronary vasculitiscardiomyopathy
spellingShingle E. S. Eniseeva
G. P. Gurtovaya
O. V. Kanya
A. A. Stefanenkova
CARDIAC LESION IN CHURG - STRAUSS SYNDROME
Acta Biomedica Scientifica
churg - strauss syndrome
hypereosinophilia
coronary vasculitis
cardiomyopathy
title CARDIAC LESION IN CHURG - STRAUSS SYNDROME
title_full CARDIAC LESION IN CHURG - STRAUSS SYNDROME
title_fullStr CARDIAC LESION IN CHURG - STRAUSS SYNDROME
title_full_unstemmed CARDIAC LESION IN CHURG - STRAUSS SYNDROME
title_short CARDIAC LESION IN CHURG - STRAUSS SYNDROME
title_sort cardiac lesion in churg strauss syndrome
topic churg - strauss syndrome
hypereosinophilia
coronary vasculitis
cardiomyopathy
url https://www.actabiomedica.ru/jour/article/view/349
work_keys_str_mv AT eseniseeva cardiaclesioninchurgstrausssyndrome
AT gpgurtovaya cardiaclesioninchurgstrausssyndrome
AT ovkanya cardiaclesioninchurgstrausssyndrome
AT aastefanenkova cardiaclesioninchurgstrausssyndrome