SECRETS: Subject-efficient clinical randomized controlled trials using synthetic intervention
Background:: The parallel-group randomized controlled trial (RCT) is commonly used in Phase-3 clinical trials to establish treatment effectiveness but requires hundreds-to-thousands of subjects, making it difficult to implement, which leads to high Phase-3 trial failure rates. One approach to increa...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-04-01
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| Series: | Contemporary Clinical Trials Communications |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2451865424000127 |