Sirtuin 1 in Chronic Kidney Disease and Therapeutic Potential of Targeting Sirtuin 1

Sirtuin 1 in Chronic Kidney Disease and Therapeutic Potential of Targeting Sirtuin 1

The incidence and prevalence of chronic kidney disease (CKD) continue to increase worldwide remaining as a major public health burden. CKD eventually progresses to end-stage kidney failure and patients with CKD have high morbidity and mortality. Sirtuin 1 (SIRT1), a NAD+-dependent deacetylases, has...

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Bibliographic Details
Main Authors: Jiayi Yan, Jue Wang, John Cijiang He, Yifei Zhong
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Endocrinology
Subjects:
kidney
SIRT1
vascular calcification
chronic kidney disease
HIV infection
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.917773/full

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