Inequalities in the burden of female breast cancer in Brazil, 1990–2017
Abstract Background Breast cancer is the most frequently diagnosed cancer in women and the leading cause of cancer death among females worldwide. In recent decades, breast cancer death rates have been stable or decreasing in more developed regions; however, this has not been observed in less develop...
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| Format: | Article |
| Language: | English |
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BMC
2020-09-01
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| Series: | Population Health Metrics |
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| Online Access: | http://link.springer.com/article/10.1186/s12963-020-00212-5 |
| _version_ | 1828481399449976832 |
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| author | Maximiliano Ribeiro Guerra Mário Círio Nogueira Deborah Carvalho Malta Camila Soares Lima Côrrea Maria de Fatima Marinho de Souza Maria Paula Curado Mariana Santos Felisbino-Mendes Meghan Mooney Mohsen Naghavi Maria Teresa Bustamante-Teixeira |
| author_facet | Maximiliano Ribeiro Guerra Mário Círio Nogueira Deborah Carvalho Malta Camila Soares Lima Côrrea Maria de Fatima Marinho de Souza Maria Paula Curado Mariana Santos Felisbino-Mendes Meghan Mooney Mohsen Naghavi Maria Teresa Bustamante-Teixeira |
| author_sort | Maximiliano Ribeiro Guerra |
| collection | DOAJ |
| description | Abstract Background Breast cancer is the most frequently diagnosed cancer in women and the leading cause of cancer death among females worldwide. In recent decades, breast cancer death rates have been stable or decreasing in more developed regions; however, this has not been observed in less developed regions. This study aims to evaluate inequalities in the burden of female breast cancer in Brazil including an analysis of interregional and interstate patterns in incidence, mortality and disability-adjusted life years (DALYs) rates from 1990 to 2017, and mortality-to-incidence ratio (MIR), and their association with the Socio-demographic Index (SDI). Methods Using estimates from the global burden of disease (GBD) study, we applied a spatial exploratory analysis technique to obtain measurements of global and local spatial correlation. Percentage changes of breast cancer incidence, mortality, and DALYs rates between 1990 and 2017 were calculated, and maps were developed to show the spatial distribution of the variables. Spatial panel models were adjusted to investigate the association between rates and SDI in Brazilian states. Results In Brazil, while breast cancer mortality rate have had modest reduction (−4.45%; 95% UI: −6.97; −1.76) between 1990 and 2017, the incidence rate increased substantially (+39.99%; 95% UI: 34.90; 45.39). Breast cancer incidence and mortality rates in 1990 and 2017 were higher in regions with higher SDI, i.e., the most developed ones. While SDI increased in all Brazilian states between 1990 and 2017, notably in less developed regions, MIR decreased, more notably in more developed regions. The SDI had a positive association with incidence rate and a negative association with MIR. Conclusion Such findings suggest an improvement in breast cancer survival in the period, which may be related to a broader access to diagnostic methods and treatment. This study also revealed the inequality in breast cancer outcomes among Brazilian states and may guide public policy priorities for disease control in the country. |
| first_indexed | 2024-12-11T07:56:02Z |
| format | Article |
| id | doaj.art-dd12dc93f36d4041adc6973c863b5570 |
| institution | Directory Open Access Journal |
| issn | 1478-7954 |
| language | English |
| last_indexed | 2024-12-11T07:56:02Z |
| publishDate | 2020-09-01 |
| publisher | BMC |
| record_format | Article |
| series | Population Health Metrics |
| spelling | doaj.art-dd12dc93f36d4041adc6973c863b55702022-12-22T01:15:13ZengBMCPopulation Health Metrics1478-79542020-09-0118S111310.1186/s12963-020-00212-5Inequalities in the burden of female breast cancer in Brazil, 1990–2017Maximiliano Ribeiro Guerra0Mário Círio Nogueira1Deborah Carvalho Malta2Camila Soares Lima Côrrea3Maria de Fatima Marinho de Souza4Maria Paula Curado5Mariana Santos Felisbino-Mendes6Meghan Mooney7Mohsen Naghavi8Maria Teresa Bustamante-Teixeira9Graduate Program in Public Health, Universidade Federal de Juiz de Fora (UFJF)Graduate Program in Public Health, Universidade Federal de Juiz de Fora (UFJF)Department of Maternal and Child Nursing and Public Health, Nursing School, Universidade Federal de Minas Gerais (UFMG)Graduate Program in Public Health, Universidade Federal de Juiz de Fora (UFJF)Graduate Program of the Preventive Medicine Department, Medical School, Universidade Federal de Minas Gerais (UFMG)AC Camargo Cancer Center, AC Camargo HospitalDepartment of Maternal and Child Nursing and Public Health, Nursing School, Universidade Federal de Minas Gerais (UFMG)Institute for Health Metrics and Evaluation (IHME), University of WashingtonInstitute for Health Metrics and Evaluation (IHME), University of WashingtonGraduate Program in Public Health, Universidade Federal de Juiz de Fora (UFJF)Abstract Background Breast cancer is the most frequently diagnosed cancer in women and the leading cause of cancer death among females worldwide. In recent decades, breast cancer death rates have been stable or decreasing in more developed regions; however, this has not been observed in less developed regions. This study aims to evaluate inequalities in the burden of female breast cancer in Brazil including an analysis of interregional and interstate patterns in incidence, mortality and disability-adjusted life years (DALYs) rates from 1990 to 2017, and mortality-to-incidence ratio (MIR), and their association with the Socio-demographic Index (SDI). Methods Using estimates from the global burden of disease (GBD) study, we applied a spatial exploratory analysis technique to obtain measurements of global and local spatial correlation. Percentage changes of breast cancer incidence, mortality, and DALYs rates between 1990 and 2017 were calculated, and maps were developed to show the spatial distribution of the variables. Spatial panel models were adjusted to investigate the association between rates and SDI in Brazilian states. Results In Brazil, while breast cancer mortality rate have had modest reduction (−4.45%; 95% UI: −6.97; −1.76) between 1990 and 2017, the incidence rate increased substantially (+39.99%; 95% UI: 34.90; 45.39). Breast cancer incidence and mortality rates in 1990 and 2017 were higher in regions with higher SDI, i.e., the most developed ones. While SDI increased in all Brazilian states between 1990 and 2017, notably in less developed regions, MIR decreased, more notably in more developed regions. The SDI had a positive association with incidence rate and a negative association with MIR. Conclusion Such findings suggest an improvement in breast cancer survival in the period, which may be related to a broader access to diagnostic methods and treatment. This study also revealed the inequality in breast cancer outcomes among Brazilian states and may guide public policy priorities for disease control in the country.http://link.springer.com/article/10.1186/s12963-020-00212-5Breast neoplasmIncidenceMortalityGlobal burden |
| spellingShingle | Maximiliano Ribeiro Guerra Mário Círio Nogueira Deborah Carvalho Malta Camila Soares Lima Côrrea Maria de Fatima Marinho de Souza Maria Paula Curado Mariana Santos Felisbino-Mendes Meghan Mooney Mohsen Naghavi Maria Teresa Bustamante-Teixeira Inequalities in the burden of female breast cancer in Brazil, 1990–2017 Population Health Metrics Breast neoplasm Incidence Mortality Global burden |
| title | Inequalities in the burden of female breast cancer in Brazil, 1990–2017 |
| title_full | Inequalities in the burden of female breast cancer in Brazil, 1990–2017 |
| title_fullStr | Inequalities in the burden of female breast cancer in Brazil, 1990–2017 |
| title_full_unstemmed | Inequalities in the burden of female breast cancer in Brazil, 1990–2017 |
| title_short | Inequalities in the burden of female breast cancer in Brazil, 1990–2017 |
| title_sort | inequalities in the burden of female breast cancer in brazil 1990 2017 |
| topic | Breast neoplasm Incidence Mortality Global burden |
| url | http://link.springer.com/article/10.1186/s12963-020-00212-5 |
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