Comparative Pharmacokinetics of Sulfadiazine and Its Metabolite N4-Acetyl Sulfadiazine in Grass Carp (<i>Ctenopharyngodon idella</i>) at Different Temperatures after Oral Administration

Comparative Pharmacokinetics of Sulfadiazine and Its Metabolite N4-Acetyl Sulfadiazine in Grass Carp (<i>Ctenopharyngodon idella</i>) at Different Temperatures after Oral Administration

In this study, the plasma pharmacokinetics and tissue disposition of sulfadiazine (SDZ) and its main metabolite, N<sub>4</sub>-acetyl sulfadiazine (ACT-SDZ), were compared between 18 and 24 °C following a single oral administration of SDZ at 50 mg/kg in grass carp (<i>Ctenopharyngo...

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Bibliographic Details
Main Authors: Ning Xu, Miao Li, Zhoumeng Lin, Xiaohui Ai
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Pharmaceutics
Subjects:
temperature
pharmacokinetics
sulfadiazine
N<sub>4</sub>-acetyl sulfadiazine
grass carp
Online Access:https://www.mdpi.com/1999-4923/14/4/712

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