Dj1 deficiency protects against atherosclerosis with anti-inflammatory response in macrophages
Abstract Inflammation is a key contributor to atherosclerosis with macrophages playing a pivotal role through the induction of oxidative stress and cytokine/chemokine secretion. DJ1, an anti-oxidant protein, has shown to paradoxically protect against chronic and acute inflammation. However, the role...
Հիմնական հեղինակներ: | Tharini Sivasubramaniyam, Jiaqi Yang, Henry S. Cheng, Alexandra Zyla, Angela Li, Rickvinder Besla, Idit Dotan, Xavier S. Revelo, Sally Yu Shi, Helen Le, Stephanie A. Schroer, David W. Dodington, Yoo Jin Park, Min Jeong Kim, Daniella Febbraro, Isabelle Ruel, Jacques Genest, Raymond H. Kim, Tak W. Mak, Daniel A. Winer, Clinton S. Robbins, Minna Woo |
---|---|
Ձևաչափ: | Հոդված |
Լեզու: | English |
Հրապարակվել է: |
Nature Portfolio
2021-02-01
|
Շարք: | Scientific Reports |
Առցանց հասանելիություն: | https://doi.org/10.1038/s41598-021-84063-6 |
Նմանատիպ նյութեր
-
Macrophage JAK2 deficiency protects against high-fat diet-induced inflammation
: Harsh R. Desai, և այլն
Հրապարակվել է: (2017-08-01) -
FAK signalling controls insulin sensitivity through regulation of adipocyte survival
: Cynthia T. Luk, և այլն
Հրապարակվել է: (2017-02-01) -
In Memoriam- D.J Van Rooy
: W. Coetzee
Հրապարակվել է: (1965-03-01) -
Mesenchymal stromal (stem) cell therapy fails to improve outcomes in experimental severe influenza.
: Ilyse Darwish, և այլն
Հրապարակվել է: (2013-01-01) -
DJ-1 interacts with and regulates paraoxonase-2, an enzyme critical for neuronal survival in response to oxidative stress.
: Mohammad Parsanejad, և այլն
Հրապարակվել է: (2014-01-01)