Dj1 deficiency protects against atherosclerosis with anti-inflammatory response in macrophages
Abstract Inflammation is a key contributor to atherosclerosis with macrophages playing a pivotal role through the induction of oxidative stress and cytokine/chemokine secretion. DJ1, an anti-oxidant protein, has shown to paradoxically protect against chronic and acute inflammation. However, the role...
Автори: | Tharini Sivasubramaniyam, Jiaqi Yang, Henry S. Cheng, Alexandra Zyla, Angela Li, Rickvinder Besla, Idit Dotan, Xavier S. Revelo, Sally Yu Shi, Helen Le, Stephanie A. Schroer, David W. Dodington, Yoo Jin Park, Min Jeong Kim, Daniella Febbraro, Isabelle Ruel, Jacques Genest, Raymond H. Kim, Tak W. Mak, Daniel A. Winer, Clinton S. Robbins, Minna Woo |
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Формат: | Стаття |
Мова: | English |
Опубліковано: |
Nature Portfolio
2021-02-01
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Серія: | Scientific Reports |
Онлайн доступ: | https://doi.org/10.1038/s41598-021-84063-6 |
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