Physical activity is related to disease severity and fatigue, but not to relapse rate in persons with relapsing remitting multiple sclerosis – a self-reported questionnaire based study
IntroductionBased on theoretical models, physical activity has been introduced as a promoting method to mitigate the disease severity, fatigue and relapse rate in multiple sclerosis. The primary objective of the study was to investigate the relation between self-reported physical activity level and...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-07-01
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| Series: | Frontiers in Neurology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2023.1217000/full |
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| author | Marit L. Schlagheck Sven T. Hübner Niklas Joisten David Walzik Annette Rademacher Annette Rademacher Florian Wolf Florian Wolf Jens Bansi Jens Bansi Clemens Warnke Philipp Zimmer |
| author_facet | Marit L. Schlagheck Sven T. Hübner Niklas Joisten David Walzik Annette Rademacher Annette Rademacher Florian Wolf Florian Wolf Jens Bansi Jens Bansi Clemens Warnke Philipp Zimmer |
| author_sort | Marit L. Schlagheck |
| collection | DOAJ |
| description | IntroductionBased on theoretical models, physical activity has been introduced as a promoting method to mitigate the disease severity, fatigue and relapse rate in multiple sclerosis. The primary objective of the study was to investigate the relation between self-reported physical activity level and disease severity, fatigue and relapse rate in persons with relapsing remitting multiple sclerosis (RRMS).MethodsA survey was offered to persons with RRMS from March 2019 to August 2021 (n = 253). Physical activity level, fatigue and disease severity were determined using the Godin Leisure-Time Questionnaire (GLTEQ), the Patient Determined Disease Steps (PDDS) scale and the Fatigue Scale for Motor and Cognitive Functions (FSMC). Additionally, participants’ relapse rate was recorded.ResultsBivariate correlations revealed an inverse relation between physical activity level and PDDS (ρ = −0.279; p < 0.001) as well as between physical activity and FSMC (r = −0.213, p < 0.001), but not between physical activity and relapse rate (r = 0.033, p > 0.05). Multiple linear regression analyses explained 12.6% and 5.2% of the variance of PDDS and FSMC.ConclusionOur findings confirm a relation between self-reported physical activity, disease severity and fatigue in persons with RRMS. However, self-reported physical activity level does not seem to affect the annualised relapse rate. |
| first_indexed | 2024-03-12T20:59:26Z |
| format | Article |
| id | doaj.art-dd1c7400e6864b6eb5ec2560b551594d |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-03-12T20:59:26Z |
| publishDate | 2023-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-dd1c7400e6864b6eb5ec2560b551594d2023-07-31T10:58:18ZengFrontiers Media S.A.Frontiers in Neurology1664-22952023-07-011410.3389/fneur.2023.12170001217000Physical activity is related to disease severity and fatigue, but not to relapse rate in persons with relapsing remitting multiple sclerosis – a self-reported questionnaire based studyMarit L. Schlagheck0Sven T. Hübner1Niklas Joisten2David Walzik3Annette Rademacher4Annette Rademacher5Florian Wolf6Florian Wolf7Jens Bansi8Jens Bansi9Clemens Warnke10Philipp Zimmer11Division of Performance and Health, Institute for Sport and Sport Science, Technical University Dortmund, Dortmund, GermanyDepartment for Molecular and Cellular Sports Medicine, Institute for Cardiovascular Research and Sports Medicine, German Sport University Cologne, Cologne, GermanyDivision of Performance and Health, Institute for Sport and Sport Science, Technical University Dortmund, Dortmund, GermanyDivision of Performance and Health, Institute for Sport and Sport Science, Technical University Dortmund, Dortmund, GermanyDepartment for Molecular and Cellular Sports Medicine, Institute for Cardiovascular Research and Sports Medicine, German Sport University Cologne, Cologne, GermanyMarianne-Strauß-Klinik, Behandlungszentrum Kempfenhausen für Multiple Sklerose Kranke gGmbH, Berg, GermanyDepartment for Molecular and Cellular Sports Medicine, Institute for Cardiovascular Research and Sports Medicine, German Sport University Cologne, Cologne, GermanyNeurological Rehabilitation Centre Godeshöhe, Bonn, GermanyDepartment of Research and Development, Kliniken Valens, Valens, SwitzerlandDepartment of Health, OST – Eastern Swiss University of Applied Sciences, St. Gallen, SwitzerlandDepartment of Neurology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, GermanyDivision of Performance and Health, Institute for Sport and Sport Science, Technical University Dortmund, Dortmund, GermanyIntroductionBased on theoretical models, physical activity has been introduced as a promoting method to mitigate the disease severity, fatigue and relapse rate in multiple sclerosis. The primary objective of the study was to investigate the relation between self-reported physical activity level and disease severity, fatigue and relapse rate in persons with relapsing remitting multiple sclerosis (RRMS).MethodsA survey was offered to persons with RRMS from March 2019 to August 2021 (n = 253). Physical activity level, fatigue and disease severity were determined using the Godin Leisure-Time Questionnaire (GLTEQ), the Patient Determined Disease Steps (PDDS) scale and the Fatigue Scale for Motor and Cognitive Functions (FSMC). Additionally, participants’ relapse rate was recorded.ResultsBivariate correlations revealed an inverse relation between physical activity level and PDDS (ρ = −0.279; p < 0.001) as well as between physical activity and FSMC (r = −0.213, p < 0.001), but not between physical activity and relapse rate (r = 0.033, p > 0.05). Multiple linear regression analyses explained 12.6% and 5.2% of the variance of PDDS and FSMC.ConclusionOur findings confirm a relation between self-reported physical activity, disease severity and fatigue in persons with RRMS. However, self-reported physical activity level does not seem to affect the annualised relapse rate.https://www.frontiersin.org/articles/10.3389/fneur.2023.1217000/fullmultiple sclerosisphysical activitydisease severityfatiguerelapsing remitting multiple sclerosis |
| spellingShingle | Marit L. Schlagheck Sven T. Hübner Niklas Joisten David Walzik Annette Rademacher Annette Rademacher Florian Wolf Florian Wolf Jens Bansi Jens Bansi Clemens Warnke Philipp Zimmer Physical activity is related to disease severity and fatigue, but not to relapse rate in persons with relapsing remitting multiple sclerosis – a self-reported questionnaire based study Frontiers in Neurology multiple sclerosis physical activity disease severity fatigue relapsing remitting multiple sclerosis |
| title | Physical activity is related to disease severity and fatigue, but not to relapse rate in persons with relapsing remitting multiple sclerosis – a self-reported questionnaire based study |
| title_full | Physical activity is related to disease severity and fatigue, but not to relapse rate in persons with relapsing remitting multiple sclerosis – a self-reported questionnaire based study |
| title_fullStr | Physical activity is related to disease severity and fatigue, but not to relapse rate in persons with relapsing remitting multiple sclerosis – a self-reported questionnaire based study |
| title_full_unstemmed | Physical activity is related to disease severity and fatigue, but not to relapse rate in persons with relapsing remitting multiple sclerosis – a self-reported questionnaire based study |
| title_short | Physical activity is related to disease severity and fatigue, but not to relapse rate in persons with relapsing remitting multiple sclerosis – a self-reported questionnaire based study |
| title_sort | physical activity is related to disease severity and fatigue but not to relapse rate in persons with relapsing remitting multiple sclerosis a self reported questionnaire based study |
| topic | multiple sclerosis physical activity disease severity fatigue relapsing remitting multiple sclerosis |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2023.1217000/full |
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