Combinations of host biomarkers predict mortality among Ugandan children with severe malaria: a retrospective case-control study.

Severe malaria is a leading cause of childhood mortality in Africa. However, at presentation, it is difficult to predict which children with severe malaria are at greatest risk of death. Dysregulated host inflammatory responses and endothelial activation play central roles in severe malaria pathogen...

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Main Authors: Laura K Erdman, Aggrey Dhabangi, Charles Musoke, Andrea L Conroy, Michael Hawkes, Sarah Higgins, Nimerta Rajwans, Kayla T Wolofsky, David L Streiner, W Conrad Liles, Christine M Cserti-Gazdewich, Kevin C Kain
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3045453?pdf=render