Regulation of the Tumor-Suppressor Function of the Class III Phosphatidylinositol 3-Kinase Complex by Ubiquitin and SUMO

The occurrence of cancer is often associated with a dysfunction in one of the three central membrane-involution processes—autophagy, endocytosis or cytokinesis. Interestingly, all three pathways are controlled by the same central signaling module: the class III phosphatidylinositol 3-kinase (PI3K-II...

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Bibliographic Details
Main Authors: Christina Reidick, Fouzi El Magraoui, Helmut E. Meyer, Harald Stenmark, Harald W. Platta
Format: Article
Language:English
Published: MDPI AG 2014-12-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/7/1/1