Integrated Mechanisms of Polarity–Based Extracts of <i>Cucumis melo</i> L. Seed Kernels for Airway Smooth Muscle Relaxation via Key Signaling Pathways Based on WGCNA, In Vivo, and In Vitro Analyses

Integrated Mechanisms of Polarity–Based Extracts of <i>Cucumis melo</i> L. Seed Kernels for Airway Smooth Muscle Relaxation via Key Signaling Pathways Based on WGCNA, In Vivo, and In Vitro Analyses

The present study aimed to determine the mechanisms responsible for calcium–mediated smooth muscle contractions in <i>C. melo</i> seeds. The phytochemicals of <i>C. melo</i> were identified and quantified with the aid of Liquid Chromatography Electrospray Ionization Tandem Ma...

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Bibliographic Details
Main Authors: Muqeet Wahid, Fatima Saqib, Anam Ali, Abdulrahman Alshammari, Metab Alharbi, Abdur Rauf, Mohammad S. Mubarak
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Pharmaceuticals
Subjects:
<i>Cucumis melo</i>
asthma
airway smooth muscle
WGCNA
LC/ESI–MS/MS
calcium–mediated smooth muscle contraction
Online Access:https://www.mdpi.com/1424-8247/15/12/1522

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