Short- and Long-Term Outcomes in Elderly Patients Following Hand-Assisted Laparoscopic Surgery for Colorectal Liver Metastasis
(1) Background: Hand-assisted laparoscopic surgery (HALS) has engendered growing attention as a safe procedure for the resection of metastatic liver disease. However, there is little data available regarding the outcomes of HALS for colorectal liver metastasis (CRLM) in patients over the age of 75....
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-07-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/12/14/4785 |
| _version_ | 1797588868548001792 |
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| author | Ahmad Mahamid Omar Abu-Zaydeh Samar Mattar Esther Kazlow Dvir Froylich Muneer Sawaied Natalia Goldberg Yael Berger Eran Sadot Riad Haddad |
| author_facet | Ahmad Mahamid Omar Abu-Zaydeh Samar Mattar Esther Kazlow Dvir Froylich Muneer Sawaied Natalia Goldberg Yael Berger Eran Sadot Riad Haddad |
| author_sort | Ahmad Mahamid |
| collection | DOAJ |
| description | (1) Background: Hand-assisted laparoscopic surgery (HALS) has engendered growing attention as a safe procedure for the resection of metastatic liver disease. However, there is little data available regarding the outcomes of HALS for colorectal liver metastasis (CRLM) in patients over the age of 75. (2) Methods: We compare the short- and long-term outcomes of patients >75-years-old (defined in our study as “elderly patients” and referred to as group 1, G1), with patients <75-years-old (defined in our study as “younger patients” and referred to as group 2, G2). (3) Results: Of 145 patients, 28 were in G1 and 117 were in G2. The most common site of the primary tumor was the right colon in G1, and the left colon in G2 (<i>p</i> = 0.05). More patients in G1 underwent laparoscopic anterior segment resection compared with G2 (43% vs. 39% respectively) (<i>p</i> = 0.003). 53% of patients in G1 and 74% of patients in G2 completed neoadjuvant therapy (<i>p</i> = 0.04). The median size of the largest metastasis was 32 (IQR 19–52) mm in G1 and 20 (IQR 13–35) mm in G2 (<i>p</i> = 0.001). The rate of complications (Dindo-Clavien grade ≥ III) was slightly higher in G1 (<i>p</i> = 0.06). The overall 5-year survival was 30% in G1 and 52% in G2 (<i>p</i> = 0.12). (4) Conclusions: Hand-assisted laparoscopic surgery for colorectal liver metastasis is safe and effective in an elderly patient population. |
| first_indexed | 2024-03-11T00:58:08Z |
| format | Article |
| id | doaj.art-dd230671517745429dc8aa62b9bdd2d4 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-11T00:58:08Z |
| publishDate | 2023-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-dd230671517745429dc8aa62b9bdd2d42023-11-18T19:53:56ZengMDPI AGJournal of Clinical Medicine2077-03832023-07-011214478510.3390/jcm12144785Short- and Long-Term Outcomes in Elderly Patients Following Hand-Assisted Laparoscopic Surgery for Colorectal Liver MetastasisAhmad Mahamid0Omar Abu-Zaydeh1Samar Mattar2Esther Kazlow3Dvir Froylich4Muneer Sawaied5Natalia Goldberg6Yael Berger7Eran Sadot8Riad Haddad9Department of Surgery, Carmel Medical Center, Haifa 3436212, IsraelDepartment of Surgery, Carmel Medical Center, Haifa 3436212, IsraelDepartment of Surgery, Carmel Medical Center, Haifa 3436212, IsraelDepartment of Surgery, Carmel Medical Center, Haifa 3436212, IsraelDepartment of Surgery, Carmel Medical Center, Haifa 3436212, IsraelDepartment of Surgery, Carmel Medical Center, Haifa 3436212, IsraelThe Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 3200003, IsraelDepartment of Surgery, Rabin Medical Center, Petch Tikvah 4941492, IsraelDepartment of Surgery, Rabin Medical Center, Petch Tikvah 4941492, IsraelDepartment of Surgery, Carmel Medical Center, Haifa 3436212, Israel(1) Background: Hand-assisted laparoscopic surgery (HALS) has engendered growing attention as a safe procedure for the resection of metastatic liver disease. However, there is little data available regarding the outcomes of HALS for colorectal liver metastasis (CRLM) in patients over the age of 75. (2) Methods: We compare the short- and long-term outcomes of patients >75-years-old (defined in our study as “elderly patients” and referred to as group 1, G1), with patients <75-years-old (defined in our study as “younger patients” and referred to as group 2, G2). (3) Results: Of 145 patients, 28 were in G1 and 117 were in G2. The most common site of the primary tumor was the right colon in G1, and the left colon in G2 (<i>p</i> = 0.05). More patients in G1 underwent laparoscopic anterior segment resection compared with G2 (43% vs. 39% respectively) (<i>p</i> = 0.003). 53% of patients in G1 and 74% of patients in G2 completed neoadjuvant therapy (<i>p</i> = 0.04). The median size of the largest metastasis was 32 (IQR 19–52) mm in G1 and 20 (IQR 13–35) mm in G2 (<i>p</i> = 0.001). The rate of complications (Dindo-Clavien grade ≥ III) was slightly higher in G1 (<i>p</i> = 0.06). The overall 5-year survival was 30% in G1 and 52% in G2 (<i>p</i> = 0.12). (4) Conclusions: Hand-assisted laparoscopic surgery for colorectal liver metastasis is safe and effective in an elderly patient population.https://www.mdpi.com/2077-0383/12/14/4785hand-assisted laparoscopic surgerycolorectal liver metastasisoutcomeselderly patients |
| spellingShingle | Ahmad Mahamid Omar Abu-Zaydeh Samar Mattar Esther Kazlow Dvir Froylich Muneer Sawaied Natalia Goldberg Yael Berger Eran Sadot Riad Haddad Short- and Long-Term Outcomes in Elderly Patients Following Hand-Assisted Laparoscopic Surgery for Colorectal Liver Metastasis Journal of Clinical Medicine hand-assisted laparoscopic surgery colorectal liver metastasis outcomes elderly patients |
| title | Short- and Long-Term Outcomes in Elderly Patients Following Hand-Assisted Laparoscopic Surgery for Colorectal Liver Metastasis |
| title_full | Short- and Long-Term Outcomes in Elderly Patients Following Hand-Assisted Laparoscopic Surgery for Colorectal Liver Metastasis |
| title_fullStr | Short- and Long-Term Outcomes in Elderly Patients Following Hand-Assisted Laparoscopic Surgery for Colorectal Liver Metastasis |
| title_full_unstemmed | Short- and Long-Term Outcomes in Elderly Patients Following Hand-Assisted Laparoscopic Surgery for Colorectal Liver Metastasis |
| title_short | Short- and Long-Term Outcomes in Elderly Patients Following Hand-Assisted Laparoscopic Surgery for Colorectal Liver Metastasis |
| title_sort | short and long term outcomes in elderly patients following hand assisted laparoscopic surgery for colorectal liver metastasis |
| topic | hand-assisted laparoscopic surgery colorectal liver metastasis outcomes elderly patients |
| url | https://www.mdpi.com/2077-0383/12/14/4785 |
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