Structural basis of ligand interaction with atypical chemokine receptor 3
The atypical chemokine receptor 3 (ACKR3) is important for cell migration in development and cancer. Here the authors combine radiolytic footprinting, disulfide trapping, mutagenesis and molecular modelling to characterize the ligand interactions and ligand-induced conformational changes in ACKR3.
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2017-01-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms14135 |