A Simulation Study of a Radiofrequency Localization System for Tracking Patient Motion in Radiotherapy

One of the most widely used tools in cancer treatment is external beam radiotherapy. However, the major risk involved in radiotherapy is excess radiation dose to healthy tissue, exacerbated by patient motion. Here, we present a simulation study of a potential radiofrequency (RF) localization system...

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Main Authors: Mark Ostyn, Siyong Kim, Woon-Hong Yeo
Format: Article
Language:English
Published: MDPI AG 2016-04-01
Series:Sensors
Subjects:
Online Access:http://www.mdpi.com/1424-8220/16/4/534
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author Mark Ostyn
Siyong Kim
Woon-Hong Yeo
author_facet Mark Ostyn
Siyong Kim
Woon-Hong Yeo
author_sort Mark Ostyn
collection DOAJ
description One of the most widely used tools in cancer treatment is external beam radiotherapy. However, the major risk involved in radiotherapy is excess radiation dose to healthy tissue, exacerbated by patient motion. Here, we present a simulation study of a potential radiofrequency (RF) localization system designed to track intrafraction motion (target motion during the radiation treatment). This system includes skin-wearable RF beacons and an external tracking system. We develop an analytical model for direction of arrival measurement with radio frequencies (GHz range) for use in a localization estimate. We use a Monte Carlo simulation to investigate the relationship between a localization estimate and angular resolution of sensors (signal receivers) in a simulated room. The results indicate that the external sensor needs an angular resolution of about 0.03 degrees to achieve millimeter-level localization accuracy in a treatment room. This fundamental study of a novel RF localization system offers the groundwork to design a radiotherapy-compatible patient positioning system for active motion compensation.
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spelling doaj.art-dd2ae33aed564430828e65a8100a22f52022-12-22T02:52:59ZengMDPI AGSensors1424-82202016-04-0116453410.3390/s16040534s16040534A Simulation Study of a Radiofrequency Localization System for Tracking Patient Motion in RadiotherapyMark Ostyn0Siyong Kim1Woon-Hong Yeo2Radiation Oncology, Medical Physics Graduate Program, School of Medicine, Virginia Commonwealth University, Richmond, VA 23298, USARadiation Oncology, Medical Physics Graduate Program, School of Medicine, Virginia Commonwealth University, Richmond, VA 23298, USADepartment of Mechanical and Nuclear Engineering, School of Engineering, Virginia Commonwealth University, Richmond, VA 23284, USAOne of the most widely used tools in cancer treatment is external beam radiotherapy. However, the major risk involved in radiotherapy is excess radiation dose to healthy tissue, exacerbated by patient motion. Here, we present a simulation study of a potential radiofrequency (RF) localization system designed to track intrafraction motion (target motion during the radiation treatment). This system includes skin-wearable RF beacons and an external tracking system. We develop an analytical model for direction of arrival measurement with radio frequencies (GHz range) for use in a localization estimate. We use a Monte Carlo simulation to investigate the relationship between a localization estimate and angular resolution of sensors (signal receivers) in a simulated room. The results indicate that the external sensor needs an angular resolution of about 0.03 degrees to achieve millimeter-level localization accuracy in a treatment room. This fundamental study of a novel RF localization system offers the groundwork to design a radiotherapy-compatible patient positioning system for active motion compensation.http://www.mdpi.com/1424-8220/16/4/534radiotherapylocalizationdirection of arrivalangulationMonte Carlo simulationintrafraction motion
spellingShingle Mark Ostyn
Siyong Kim
Woon-Hong Yeo
A Simulation Study of a Radiofrequency Localization System for Tracking Patient Motion in Radiotherapy
Sensors
radiotherapy
localization
direction of arrival
angulation
Monte Carlo simulation
intrafraction motion
title A Simulation Study of a Radiofrequency Localization System for Tracking Patient Motion in Radiotherapy
title_full A Simulation Study of a Radiofrequency Localization System for Tracking Patient Motion in Radiotherapy
title_fullStr A Simulation Study of a Radiofrequency Localization System for Tracking Patient Motion in Radiotherapy
title_full_unstemmed A Simulation Study of a Radiofrequency Localization System for Tracking Patient Motion in Radiotherapy
title_short A Simulation Study of a Radiofrequency Localization System for Tracking Patient Motion in Radiotherapy
title_sort simulation study of a radiofrequency localization system for tracking patient motion in radiotherapy
topic radiotherapy
localization
direction of arrival
angulation
Monte Carlo simulation
intrafraction motion
url http://www.mdpi.com/1424-8220/16/4/534
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