First-in-human study of a novel Upar-targeted imaging agent (FGO01) for visualization of malignant glioma during surgery

First-in-human study of a novel Upar-targeted imaging agent (FGO01) for visualization of malignant glioma during surgery

Bibliographic Details
Main Authors:	J. Skjøth-Rasmussen, A. Azam, K. Juhl, S. Ginsborg, M. Kryspin Sørensen, C. Sølling, C.C. Larsen, D. Scheie, A. Kjaer
Format:	Article
Language:	English
Published:	Elsevier 2022-01-01
Series:	Brain and Spine
Online Access:	http://www.sciencedirect.com/science/article/pii/S2772529422006403

Similar Items

Peptide-Based Optical uPAR Imaging for Surgery: In Vivo Testing of ICG-Glu-Glu-AE105.
by: Karina Juhl, et al.
Published: (2016-01-01)

Hyperlactatemia associated with elective tumor craniotomy: Protocol for an observational study of pathophysiology and clinical implications.
by: Alexandra Vassilieva, et al.
Published: (2022-01-01)

SMARTPHONE LEVEL INDOOR/OUTDOOR UBIQUITOUS PEDESTRIAN POSITIONING 3DMA GNSS/VINS INTEGRATION USING FGO
by: H.-Y. Ho, et al.
Published: (2023-05-01)

Targeting uPAR by CRISPR/Cas9 System Attenuates Cancer Malignancy and Multidrug Resistance
by: Kun Wang, et al.
Published: (2019-02-01)

Data on the regulation of moesin and merlin by the urokinase receptor (uPAR): Model explaining distal activation of integrins by uPAR
by: Bernard Degryse, et al.
Published: (2017-12-01)

Urokinase-type plasminogen activator receptor (uPAR), tissue factor (TF) and epidermal growth factor receptor (EGFR): tumor expression patterns and prognostic value in oral cancer
by: Anders Christensen, et al.
Published: (2017-08-01)

Targeted imaging of uPAR expression in vivo with cyclic AE105 variants
by: Julie Maja Leth, et al.
Published: (2023-10-01)

uPAR/cathepsin B overexpression reverse angiogenesis by rescuing FAK phosphorylation in uPAR/cathepsin B down regulated meningioma.
by: Reshu Gupta, et al.
Published: (2011-02-01)

Potential of uPAR, αvβ6 Integrin, and Tissue Factor as Targets for Molecular Imaging of Oral Squamous Cell Carcinoma: Evaluation of Nine Targets in Primary Tumors and Metastases by Immunohistochemistry
by: Mads Lawaetz, et al.
Published: (2023-02-01)

MMP-9, uPAR and cathepsin B silencing downregulate integrins in human glioma xenograft cells in vitro and in vivo in nude mice.
by: Krishna Kumar Veeravalli, et al.
Published: (2010-07-01)

The ketogenic diet for the treatment of malignant glioma
by: Eric C. Woolf, et al.
Published: (2015-01-01)

Differential Roles of uPAR in Peritoneal Ovarian Carcinomatosis
by: Nada N. Al-Hassan, et al.
Published: (2012-04-01)

Crystal structure and cellular functions of uPAR dimer
by: Shujuan Yu, et al.
Published: (2022-03-01)

Diagnostic Value of Preoperative uPAR-PET/CT in Regional Lymph Node Staging of Oral and Oropharyngeal Squamous Cell Carcinoma: A Prospective Phase II Trial
by: Mads Lawaetz, et al.
Published: (2023-10-01)

Retraction: uPAR/Cathepsin B Overexpression Reverse Angiogenesis by Rescuing FAK Phosphorylation in uPAR/Cathepsin B Down Regulated Meningioma.
by: PLOS ONE Editors
Published: (2020-01-01)

Targeted gene-expression analysis during malignant transformation in primary and secondary malignant meningioma
by: A.D. Maier, et al.
Published: (2021-01-01)

uPAR (PLAUR) Marks Two Intra-Tumoral Subtypes of Glioblastoma: Insights from Single-Cell RNA Sequencing
by: Yue He, et al.
Published: (2024-02-01)

A doxycycline-inducible urokinase receptor (uPAR) upregulates uPAR activities including resistance to anoikis in human prostate cancer cell lines
by: Reiser Jakob, et al.
Published: (2007-05-01)

uPAR EXPRESSION IN CANINE NORMAL PROSTATE AND WITH PROLIFERATIVE DISORDERS
by: Mariana Rodrigues Faleiro, et al.
Published: (2013-06-01)

Characterization and function of human Ly-6/uPAR molecules
by: Hyun Kyung Kong & Jong Hoon Park*
Published: (2012-11-01)

The urokinase receptor (uPAR) facilitates clearance of Borrelia burgdorferi.
by: Joppe W R Hovius, et al.
Published: (2009-05-01)

The uPA/uPAR system in astrocytic wound healing
by: Manuel Yepes
Published: (2022-01-01)

uPAR EXPRESSION IN CANINE NORMAL PROSTATE AND WITH PROLIFERATIVE DISORDERS
by: Mariana Rodrigues Faleiro, et al.
Published: (2013-06-01)

Downregulation of uPAR and cathepsin B induces apoptosis via regulation of Bcl-2 and Bax and inhibition of the PI3K/Akt pathway in gliomas.
by: Ramarao Malla, et al.
Published: (2010-10-01)

Urokinase-type plasminogen activator receptor (uPAR) assessed by liquid biopsies and PET/CT for prognostication in head and neck cancer patients
by: Louise Madeleine Risør, et al.
Published: (2022-11-01)

Correction: Downregulation of uPAR and Cathepsin B Induces Apoptosis via Regulation of Bcl-2 and Bax and Inhibition of the PI3K/Akt Pathway in Gliomas
Published: (2014-01-01)

Correction: Downregulation of uPAR and Cathepsin B Induces Apoptosis via Regulation of Bcl-2 and Bax and Inhibition of the PI3K/Akt Pathway in Gliomas.
by: Ramarao Malla, et al.
Published: (2014-01-01)

Retraction: Downregulation of uPAR and Cathepsin B Induces Apoptosis via Regulation of Bcl-2 and Bax and Inhibition of the PI3K/Akt Pathway in Gliomas.
by: PLOS ONE Editors
Published: (2020-01-01)

Identification of uPAR Variants Acting as ceRNAs in Leukaemia Cells
by: Mariaevelina Alfieri, et al.
Published: (2022-04-01)

New Pieces in the Puzzle of uPAR Role in Cell Migration Mechanisms
by: Anna Gorrasi, et al.
Published: (2020-11-01)

Orientational Preferences of GPI-Anchored Ly6/uPAR Proteins
by: Maxim M. Zaigraev, et al.
Published: (2022-12-01)

The uPAR System as a Potential Therapeutic Target in the Diseased Eye
by: Maurizio Cammalleri, et al.
Published: (2019-08-01)

Functional characterization of αMβ2-uPar interaction
by: Tang, Manli
Published: (2010)

Clathrin and LRP-1-independent constitutive endocytosis and recycling of uPAR.
by: Katia Cortese, et al.
Published: (2008-01-01)

Prognostic value of uPAR expression and angiogenesis in primary and metastatic melanoma.
by: Emilia Hugdahl, et al.
Published: (2019-01-01)

Awake Laser Interstitial Thermal Therapy in the Treatment of Brain Tumors and Epilepsy
by: Silas Haahr Nielsen, et al.
Published: (2023-01-01)

Co-depletion of cathepsin B and uPAR induces G0/G1 arrest in glioma via FOXO3a mediated p27 upregulation.
by: Sreelatha Gopinath, et al.
Published: (2010-07-01)

Fusion Genes Altered in Adult Malignant Gliomas
by: Gan You, et al.
Published: (2021-10-01)

Surgically Induced Contrast Enhancements on Intraoperative and Early Postoperative MRI Following High-Grade Glioma Surgery: A Systematic Review
by: Alexander Malcolm Rykkje, et al.
Published: (2021-07-01)

Tumor Metabolism of Malignant Gliomas
by: Deliang Guo, et al.
Published: (2013-11-01)