Aplastic anemia during pregnancy: a review of obstetric and anesthetic considerations
Efrain Riveros-Perez,1 Amy C Hermesch,2 Linda A Barbour,3 Joy L Hawkins4 1Department of Anesthesiology and Perioperative Medicine, Medical College of Georgia, Augusta University, Augusta, GA, 2Maternal Fetal Medicine, 3Obstetrics and Gynecology, 4Department of Anesthesiology, University of Colorado...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2018-02-01
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| Series: | International Journal of Women's Health |
| Subjects: | |
| Online Access: | https://www.dovepress.com/aplastic-anemia-during-pregnancy-a-review-of-obstetric-and-anesthetic--peer-reviewed-article-IJWH |
| _version_ | 1818178607076343808 |
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| author | Riveros-Perez E Hermesch AC Barbour LA Hawkins JL |
| author_facet | Riveros-Perez E Hermesch AC Barbour LA Hawkins JL |
| author_sort | Riveros-Perez E |
| collection | DOAJ |
| description | Efrain Riveros-Perez,1 Amy C Hermesch,2 Linda A Barbour,3 Joy L Hawkins4 1Department of Anesthesiology and Perioperative Medicine, Medical College of Georgia, Augusta University, Augusta, GA, 2Maternal Fetal Medicine, 3Obstetrics and Gynecology, 4Department of Anesthesiology, University of Colorado School of Medicine, Aurora, CO, USA Abstract: Aplastic anemia is a hematologic condition occasionally presenting during pregnancy. This pathological process is associated with significant maternal and neonatal morbidity and mortality. Obstetric and anesthetic management is challenging, and treatment requires a coordinated effort by an interdisciplinary team, in order to provide safe care to these patients. In this review, we describe the current state of the literature as it applies to the complexity of aplastic anemia in pregnancy, focusing on pathophysiologic aspects of the disease in pregnancy, as well as relevant obstetric and anesthetic considerations necessary to treat this challenging problem. A multidisciplinary-team approach to the management of aplastic anemia in pregnancy is necessary to coordinate prenatal care, optimize maternofetal outcomes, and plan peripartum interventions. Conservative transfusion management is critical to prevent alloimmunization. Although a safe threshold-platelet count for neuraxial anesthesia has not been established, selection of anesthetic technique must be evaluated on a case-to-case basis. Keywords: aplastic anemia, platelets, high-risk obstetrics, obstetric anesthesia, pregnancy |
| first_indexed | 2024-12-11T20:50:40Z |
| format | Article |
| id | doaj.art-dd2c95b89f0e49cb99fd35a947d1ab9a |
| institution | Directory Open Access Journal |
| issn | 1179-1411 |
| language | English |
| last_indexed | 2024-12-11T20:50:40Z |
| publishDate | 2018-02-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | International Journal of Women's Health |
| spelling | doaj.art-dd2c95b89f0e49cb99fd35a947d1ab9a2022-12-22T00:51:14ZengDove Medical PressInternational Journal of Women's Health1179-14112018-02-01Volume 1011712536982Aplastic anemia during pregnancy: a review of obstetric and anesthetic considerationsRiveros-Perez EHermesch ACBarbour LAHawkins JLEfrain Riveros-Perez,1 Amy C Hermesch,2 Linda A Barbour,3 Joy L Hawkins4 1Department of Anesthesiology and Perioperative Medicine, Medical College of Georgia, Augusta University, Augusta, GA, 2Maternal Fetal Medicine, 3Obstetrics and Gynecology, 4Department of Anesthesiology, University of Colorado School of Medicine, Aurora, CO, USA Abstract: Aplastic anemia is a hematologic condition occasionally presenting during pregnancy. This pathological process is associated with significant maternal and neonatal morbidity and mortality. Obstetric and anesthetic management is challenging, and treatment requires a coordinated effort by an interdisciplinary team, in order to provide safe care to these patients. In this review, we describe the current state of the literature as it applies to the complexity of aplastic anemia in pregnancy, focusing on pathophysiologic aspects of the disease in pregnancy, as well as relevant obstetric and anesthetic considerations necessary to treat this challenging problem. A multidisciplinary-team approach to the management of aplastic anemia in pregnancy is necessary to coordinate prenatal care, optimize maternofetal outcomes, and plan peripartum interventions. Conservative transfusion management is critical to prevent alloimmunization. Although a safe threshold-platelet count for neuraxial anesthesia has not been established, selection of anesthetic technique must be evaluated on a case-to-case basis. Keywords: aplastic anemia, platelets, high-risk obstetrics, obstetric anesthesia, pregnancy https://www.dovepress.com/aplastic-anemia-during-pregnancy-a-review-of-obstetric-and-anesthetic--peer-reviewed-article-IJWHAplastic anemiaplateletsHigh-risk obstetricsObstetric anesthesia |
| spellingShingle | Riveros-Perez E Hermesch AC Barbour LA Hawkins JL Aplastic anemia during pregnancy: a review of obstetric and anesthetic considerations International Journal of Women's Health Aplastic anemia platelets High-risk obstetrics Obstetric anesthesia |
| title | Aplastic anemia during pregnancy: a review of obstetric and anesthetic considerations |
| title_full | Aplastic anemia during pregnancy: a review of obstetric and anesthetic considerations |
| title_fullStr | Aplastic anemia during pregnancy: a review of obstetric and anesthetic considerations |
| title_full_unstemmed | Aplastic anemia during pregnancy: a review of obstetric and anesthetic considerations |
| title_short | Aplastic anemia during pregnancy: a review of obstetric and anesthetic considerations |
| title_sort | aplastic anemia during pregnancy a review of obstetric and anesthetic considerations |
| topic | Aplastic anemia platelets High-risk obstetrics Obstetric anesthesia |
| url | https://www.dovepress.com/aplastic-anemia-during-pregnancy-a-review-of-obstetric-and-anesthetic--peer-reviewed-article-IJWH |
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