Synthetic Biology Open Language (SBOL) Version 2.0.0
Synthetic biology builds upon the techniques and successes of genetics, molecular biology, and metabolic engineering by applying engineering principles to the design of biological systems. The field still faces substantial challenges, including long development times, high rates of failure, and poor...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2015-06-01
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| Series: | Journal of Integrative Bioinformatics |
| Online Access: | https://doi.org/10.1515/jib-2015-272 |
| _version_ | 1818582210531295232 |
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| author | Bartley Bryan Beal Jacob Clancy Kevin Misirli Goksel Roehner Nicholas Oberortner Ernst Pocock Matthew Bissell Michael Madsen Curtis Nguyen Tramy Zhang Zhen Gennari John H. Myers Chris Wipat Anil Sauro Herbert |
| author_facet | Bartley Bryan Beal Jacob Clancy Kevin Misirli Goksel Roehner Nicholas Oberortner Ernst Pocock Matthew Bissell Michael Madsen Curtis Nguyen Tramy Zhang Zhen Gennari John H. Myers Chris Wipat Anil Sauro Herbert |
| author_sort | Bartley Bryan |
| collection | DOAJ |
| description | Synthetic biology builds upon the techniques and successes of genetics, molecular biology, and metabolic engineering by applying engineering principles to the design of biological systems. The field still faces substantial challenges, including long development times, high rates of failure, and poor reproducibility. One method to ameliorate these problems would be to improve the exchange of information about designed systems between laboratories. The Synthetic Biology Open Language (SBOL) has been developed as a standard to support the specification and exchange of biological design information in synthetic biology, filling a need not satisfied by other pre-existing standards. This document details version 2.0 of SBOL, introducing a standardized format for the electronic exchange of information on the structural and functional aspects of biological designs. The standard has been designed to support the explicit and unambiguous description of biological designs by means of a well defined data model. The standard also includes rules and best practices on how to use this data model and populate it with relevant design details. The publication of this specification is intended to make these capabilities more widely accessible to potential developers and users in the synthetic biology community and beyond. |
| first_indexed | 2024-12-16T07:45:46Z |
| format | Article |
| id | doaj.art-dd31aec2c9ee4fc08ab9946ad18c80b0 |
| institution | Directory Open Access Journal |
| issn | 1613-4516 |
| language | English |
| last_indexed | 2024-12-16T07:45:46Z |
| publishDate | 2015-06-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Journal of Integrative Bioinformatics |
| spelling | doaj.art-dd31aec2c9ee4fc08ab9946ad18c80b02022-12-21T22:38:59ZengDe GruyterJournal of Integrative Bioinformatics1613-45162015-06-0112290299110.1515/jib-2015-272jib-2015-272Synthetic Biology Open Language (SBOL) Version 2.0.0Bartley Bryan0Beal Jacob1Clancy Kevin2Misirli Goksel3Roehner Nicholas4Oberortner Ernst5Pocock Matthew6Bissell Michael7Madsen Curtis8Nguyen Tramy9Zhang Zhen10Gennari John H.11Myers Chris12Wipat Anil13Sauro Herbert14University of Washington, Seattle, United States of AmericaRaytheon BBN Technologies, Cambridge, United States of AmericaThermoFisher Scientific, Waltham, United States of AmericaNewcastle University, Newcastle, United Kingdom of Great Britain and Northern IrelandBoston University, Boston, United States of AmericaDOE Joint Genome Institute, Walnut Creek, United States of AmericaNewcastle University, Newcastle, United Kingdom of Great Britain and Northern IrelandAmyris, Inc., Emeryville, United States of AmericaNewcastle University, Newcastle, United Kingdom of Great Britain and Northern IrelandUniversity of Utah, Salt Lake City, United States of AmericaUniversity of Utah, Salt Lake City, United States of AmericaUniversity of Washington, Seattle, United States of AmericaUniversity of Utah, Salt Lake City, United States of AmericaNewcastle University, Newcastle, United Kingdom of Great Britain and Northern IrelandUniversity of Washington, Seattle, United States of AmericaSynthetic biology builds upon the techniques and successes of genetics, molecular biology, and metabolic engineering by applying engineering principles to the design of biological systems. The field still faces substantial challenges, including long development times, high rates of failure, and poor reproducibility. One method to ameliorate these problems would be to improve the exchange of information about designed systems between laboratories. The Synthetic Biology Open Language (SBOL) has been developed as a standard to support the specification and exchange of biological design information in synthetic biology, filling a need not satisfied by other pre-existing standards. This document details version 2.0 of SBOL, introducing a standardized format for the electronic exchange of information on the structural and functional aspects of biological designs. The standard has been designed to support the explicit and unambiguous description of biological designs by means of a well defined data model. The standard also includes rules and best practices on how to use this data model and populate it with relevant design details. The publication of this specification is intended to make these capabilities more widely accessible to potential developers and users in the synthetic biology community and beyond.https://doi.org/10.1515/jib-2015-272 |
| spellingShingle | Bartley Bryan Beal Jacob Clancy Kevin Misirli Goksel Roehner Nicholas Oberortner Ernst Pocock Matthew Bissell Michael Madsen Curtis Nguyen Tramy Zhang Zhen Gennari John H. Myers Chris Wipat Anil Sauro Herbert Synthetic Biology Open Language (SBOL) Version 2.0.0 Journal of Integrative Bioinformatics |
| title | Synthetic Biology Open Language (SBOL) Version 2.0.0 |
| title_full | Synthetic Biology Open Language (SBOL) Version 2.0.0 |
| title_fullStr | Synthetic Biology Open Language (SBOL) Version 2.0.0 |
| title_full_unstemmed | Synthetic Biology Open Language (SBOL) Version 2.0.0 |
| title_short | Synthetic Biology Open Language (SBOL) Version 2.0.0 |
| title_sort | synthetic biology open language sbol version 2 0 0 |
| url | https://doi.org/10.1515/jib-2015-272 |
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