Abnormal Promoter Methylation of Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) Gene in the Pathogenesis of Crohn’s Disease

Abnormal Promoter Methylation of Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) Gene in the Pathogenesis of Crohn’s Disease

Changes in the expression of nucleotide-binding oligomerization domain containing 2 (NOD2) play an important role in the pathogenesis of several autoimmune diseases, such as inflammatory bowel diseases (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC). It seems that epigenetic modif...

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Bibliographic Details
Main Authors: Golshid Sanati, Mehrdad Noruzinia, Davood Jafari, Mohammad Ahmadvand, Shahram Teimourian, Naser Ebrahimi Daryani, Nima Rezaei
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2023-08-01
Series:Acta Medica Iranica
Subjects:
Nucleotide-binding oligomerization domain containing 2 (NOD2)
Inflammatory bowel disease
Crohn’s disease
DNA methylation
Online Access:https://acta.tums.ac.ir/index.php/acta/article/view/9867

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