Establish of a mouse model of COPD that meets clinical criteria by LPS+cigarette smoke exposure for 12 weeks

Establish of a mouse model of COPD that meets clinical criteria by LPS+cigarette smoke exposure for 12 weeks

Objective To investigate whether the induction of lipopolysaccharide (LPS) combined with cigarette smoke (CS) for 12 weeks can successfully construct a mouse model of chronic obstructive pulmonary disease (COPD) that meets clinical criteria. Methods Thirty male C57BL/6 mice (8 weeks old, 20~25 g) we...

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Bibliographic Details
Main Authors: LI Wu, LIU Yunhua, SHI Tuo, DAI Xiaotian, DENG Guohong, XIONG Wei
Format: Article
Language:zho
Published: Editorial Office of Journal of Army Medical University 2023-05-01
Series:陆军军医大学学报
Subjects:
cigarette smoke
lipopolysaccharide
chronic obstructive pulmonary disease
clinical criteria
Online Access:http://aammt.tmmu.edu.cn/html/202301084.htm

Internet

http://aammt.tmmu.edu.cn/html/202301084.htm

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