The impact of splenectomy on human lipid metabolism
Background: Splenectomy impacts hematological, immunological, and metabolic functions of the patient. Since our understanding of its metabolic effects, in particular effects on lipid metabolism, is limited, this study aims to investigate the effects of splenectomy on lipid metabolism. Methods: The d...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Upsala Medical Society
2022-06-01
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| Series: | Upsala Journal of Medical Sciences |
| Subjects: | |
| Online Access: | https://ujms.net/index.php/ujms/article/view/8500/14654 |
| _version_ | 1797712510866948096 |
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| author | Orgun Gunes Emre Turgut Yusuf Murat Bag Ersin Gundoğan Ajda Gunes Fatih Sumer |
| author_facet | Orgun Gunes Emre Turgut Yusuf Murat Bag Ersin Gundoğan Ajda Gunes Fatih Sumer |
| author_sort | Orgun Gunes |
| collection | DOAJ |
| description | Background: Splenectomy impacts hematological, immunological, and metabolic functions of the patient. Since our understanding of its metabolic effects, in particular effects on lipid metabolism, is limited, this study aims to investigate the effects of splenectomy on lipid metabolism. Methods: The data from 316 patients undergoing splenectomy between 2009 and 2019 were retrospectively analyzed. Thirty-eight patients whose serum lipid values were measured both preoperatively and 1 year after surgery were included in this study. Results: Significantly higher levels of total cholesterol, low-density lipoprotein (LDL), and non-high-density lipoprotein (HDL) lipid profile were found in the postsplenectomy measurements. However, no significant differences were recorded in levels of triglyceride, HDL, or very-LDL. Conclusion: We determined that splenectomy does impact lipid metabolism, and that the metabolic effects of splenectomy should further be investigated. |
| first_indexed | 2024-03-12T07:22:42Z |
| format | Article |
| id | doaj.art-dd3370a0ac0348a590a3329a8341a83e |
| institution | Directory Open Access Journal |
| issn | 0300-9734 2000-1967 |
| language | English |
| last_indexed | 2024-03-12T07:22:42Z |
| publishDate | 2022-06-01 |
| publisher | Upsala Medical Society |
| record_format | Article |
| series | Upsala Journal of Medical Sciences |
| spelling | doaj.art-dd3370a0ac0348a590a3329a8341a83e2023-09-02T22:17:04ZengUpsala Medical SocietyUpsala Journal of Medical Sciences0300-97342000-19672022-06-011271410.48101/ujms.v127.85008500The impact of splenectomy on human lipid metabolismOrgun Gunes0Emre Turgut1Yusuf Murat Bag2Ersin Gundoğan3Ajda Gunes4Fatih Sumer5Department of Gastrointestinal Surgery, Atatürk Training and Research Hospital, Izmir, TurkeyDepartment of Gastrointestinal Surgery, Inonu University Turgut Ozal Medical Center, Malatya, TurkeyDepartment of Gastrointestinal Surgery, Van Training and Research Hospital, Van, TurkeyDepartment of Gastrointestinal Surgery, Kayseri Training and Research Hospital, Kayseri, TurkeyDepartment of Hematology, Ege University, Izmir, TurkeyDepartment of Gastrointestinal Surgery, Irmet Hospital, Tekirdağ, TurkeyBackground: Splenectomy impacts hematological, immunological, and metabolic functions of the patient. Since our understanding of its metabolic effects, in particular effects on lipid metabolism, is limited, this study aims to investigate the effects of splenectomy on lipid metabolism. Methods: The data from 316 patients undergoing splenectomy between 2009 and 2019 were retrospectively analyzed. Thirty-eight patients whose serum lipid values were measured both preoperatively and 1 year after surgery were included in this study. Results: Significantly higher levels of total cholesterol, low-density lipoprotein (LDL), and non-high-density lipoprotein (HDL) lipid profile were found in the postsplenectomy measurements. However, no significant differences were recorded in levels of triglyceride, HDL, or very-LDL. Conclusion: We determined that splenectomy does impact lipid metabolism, and that the metabolic effects of splenectomy should further be investigated.https://ujms.net/index.php/ujms/article/view/8500/14654atherosclerosishyperlipidemiaautotransplantationhomeostasiscoronarylipoprotein |
| spellingShingle | Orgun Gunes Emre Turgut Yusuf Murat Bag Ersin Gundoğan Ajda Gunes Fatih Sumer The impact of splenectomy on human lipid metabolism Upsala Journal of Medical Sciences atherosclerosis hyperlipidemia autotransplantation homeostasis coronary lipoprotein |
| title | The impact of splenectomy on human lipid metabolism |
| title_full | The impact of splenectomy on human lipid metabolism |
| title_fullStr | The impact of splenectomy on human lipid metabolism |
| title_full_unstemmed | The impact of splenectomy on human lipid metabolism |
| title_short | The impact of splenectomy on human lipid metabolism |
| title_sort | impact of splenectomy on human lipid metabolism |
| topic | atherosclerosis hyperlipidemia autotransplantation homeostasis coronary lipoprotein |
| url | https://ujms.net/index.php/ujms/article/view/8500/14654 |
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